KinCore

Ligand: 4ZQ

Total number of chains: 2

Spatial label	Dihedral label	Number of Chains	Representative
DFGin	BLAminus	2	5CAVA

Database table as tsv

Family	Gene	UniprotID	PDB	Resolution	Activity	Spatial-Dihedral	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Unresolved residues in A-loop	Phosphorylation	Mutation	Protein
TYR	EGFR	EGFR_HUMAN	5CAVA	2.73	Active	DFGin‑BLAminus	in-in	in-in	4ZQ	Type1	697 - 1020	0	None	None	Epidermal growth factor receptor
TYR	EGFR	EGFR_HUMAN	5CASA	2.1	None	DFGin‑BLAminus	in-in	in-none	4ZQ	Type1.5_Back	696 - 1019	13	None	T790M,L858R,E865A,E866A,K867A	Epidermal growth factor receptor

Ligand: 4ZQ

Total number of chains: 2

Spatial label	Dihedral label	Number of Chains	Representative
DFGin	BLAminus	2	5CAVA

Database table as tsv

Family	Gene	UniprotID	PDB	Resolution	Activity	Spatial-Dihedral	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Unresolved residues in A-loop	Phosphorylation	Mutation	Protein	Organism
TYR	EGFR	EGFR_HUMAN	5CAVA	2.73	Active	DFGin‑BLAminus	in-in	in-in	4ZQ	Type1	697 - 1020	0	None	None	Epidermal growth factor receptor	Homo sapiens
TYR	EGFR	EGFR_HUMAN	5CASA	2.1	None	DFGin‑BLAminus	in-in	in-none	4ZQ	Type1.5_Back	696 - 1019	13	None	T790M,L858R,E865A,E866A,K867A	Epidermal growth factor receptor	Homo sapiens

Ligand: 4ZQ

Total number of chains: 0

Spatial label	Dihedral label	Number of Chains	Representative

Database table as tsv

Family	Gene	UniprotID	PDB	Resolution	Activity	Spatial-Dihedral	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Unresolved residues in A-loop	Phosphorylation	Mutation	Protein	Organism