| Family | Gene | UniprotID | PDB | Resolution | Activity | Spatial-Dihedral | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop | Phosphorylation | Mutation | Protein |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | EGFR | EGFR_HUMAN | 7UKWA | 2.6 | Inactive | DFGin‑BLBplus | out-out | out-out | No_ligand | No_ligand | 702 - 1014 | 2 | None | T790M,V948R | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 7UKWD | 2.6 | Inactive | DFGin‑BLBtrans | out-out | out-none | No_ligand | No_ligand | 702 - 1012 | 6 | None | T790M,V948R | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 7UKWB | 2.6 | Inactive | DFGin‑BLBtrans | out-out | none-none | ZRT | Type1 | 702 - 1010 | 17 | None | T790M,V948R | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 7UKWC | 2.6 | Inactive | DFGin‑BLBtrans | out-out | out-none | ZRT | Type1 | 700 - 1005 | 13 | None | T790M,V948R | Epidermal growth factor receptor |
| Family | Gene | UniprotID | PDB | Resolution | Activity | Spatial-Dihedral | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop | Phosphorylation | Mutation | Protein | Organism |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | EGFR | EGFR_HUMAN | 7UKWA | 2.6 | Inactive | DFGin‑BLBplus | out-out | out-out | No_ligand | No_ligand | 702 - 1014 | 2 | None | T790M,V948R | Epidermal growth factor receptor | Homo sapiens |
| TYR | EGFR | EGFR_HUMAN | 7UKWD | 2.6 | Inactive | DFGin‑BLBtrans | out-out | out-none | No_ligand | No_ligand | 702 - 1012 | 6 | None | T790M,V948R | Epidermal growth factor receptor | Homo sapiens |
| TYR | EGFR | EGFR_HUMAN | 7UKWB | 2.6 | Inactive | DFGin‑BLBtrans | out-out | none-none | ZRT | Type1 | 702 - 1010 | 17 | None | T790M,V948R | Epidermal growth factor receptor | Homo sapiens |
| TYR | EGFR | EGFR_HUMAN | 7UKWC | 2.6 | Inactive | DFGin‑BLBtrans | out-out | out-none | ZRT | Type1 | 700 - 1005 | 13 | None | T790M,V948R | Epidermal growth factor receptor | Homo sapiens |
| Spatial label | Dihedral label | Number of Chains | Representative |
|---|
| Family | Gene | UniprotID | PDB | Resolution | Activity | Spatial-Dihedral | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop | Phosphorylation | Mutation | Protein | Organism |
|---|