9M41

PAK2 (Serine/threonine-protein kinase PAK 2)
Group: STE
Uniprot: PAK2_HUMAN
Organism: Homo sapiens
Domain boundary: 249 - 499
Resolu: 3.02

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGout BBAminus out-none out-out No_ligand No_ligand 85 - 520 4
B Inactive DFGout None out-none out-out No_ligand No_ligand 83 - 521 7
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
         -          -          7         17 
mgsshhhhhh ssglvprgsh masmsdngel edkppappvr 
        27         37         47         57 
msstifstgg kdplsanhsl kplpsvpeek kprhkiisif 
        67         77         87         97 
sgtekgskkk ekerpeispp sdfehTIHVG FDAVTGEFTG 
       107        117        127        137 
MPEQWARLLQ TSNITKLEQK KNPQAVLDVL KFYDSNTVkq 
       147        157        167        177 
kylsftppek dgfpsgtpal nakgteapav vteeedddee 
       187        197        207        217 
tappviaprp dhtksiytrs vidpvpapvg dshvdgaaks 
       227        237        247        257 
ldkqkkktKM TDEEIMEKLR TIVSIGDPKK KYTRYEKIGQ 
       267        277        287        297 
GASGTVFTAT DVALGQEVAI RQINLQKQPK KELIINEILV 
       307        317        327        337 
MKELKNPNIV NFLDSYLVGD ELFVVMEYLA GGSLTDVVTE 
       347        357        367        377 
TCMDEAQIAA VCRECLQALE FLHANQVIHR NIKSDNVLLG 
       387        397        407        417 
MEGSVKLTDF GFCAQITPEQ skrstmvGTP YWMAPEVVTR 
       427        437        447        457 
KAYGPKVDIW SLGIMAIEMV EGEPPYLNEN PLRALYLIAT 
       467        477        487        497 
NGTPELQNPE KLSPIFRDFL NRCLEMDVEK RGSAKELLQH 
       507        517 
PFLKLAKPLS SLTPLIMAAK EAMKsnr
Lower-case residues are disordered in structure.
Mutations: K278R,D368N
Phosphorylation: None