Ligand: 3Z5

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 1 100.0% 4X7NA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
OTHER EIF2AK3 E2AK3_HUMAN 4X7NA 2.35 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 3Z5 Type2 585 - 1087 0 None D937N Eukaryotic translation initiation factor 2-alpha kinase 3

Ligand: 3Z5

Total number of chains: 1
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 1 100.0% 4X7NA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
OTHER EIF2AK3 E2AK3_HUMAN 4X7NA 2.35 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 3Z5 Type2 585 - 1087 0 None D937N Eukaryotic translation initiation factor 2-alpha kinase 3 Homo sapiens

Ligand: 3Z5

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism