Ligand: AV9 (Tivozanib, Fotivda)

Total number of chains: 5
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 5 100.0% 4ASEA
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
STE SLK SLK_HUMAN 8BEMD 2.6 Inactive DFGout‑BBAminus out-none none-out nonTYR APEdihe_aaioi APEdist_nnno AV9 Type1 19 - 310 0 None None STE20-like serine/threonine-protein kinase
STE SLK SLK_HUMAN 8BEMG 2.6 Inactive DFGout‑BBAminus out-none none-out nonTYR APEdihe_aaioi APEdist_nnno AV9 Type1 19 - 309 0 None None STE20-like serine/threonine-protein kinase
STE SLK SLK_HUMAN 8BEMA 2.6 Inactive DFGout‑BBAminus out-none none-out nonTYR APEdihe_aaioi APEdist_nnno AV9 Type1.5_Front 19 - 309 0 None None STE20-like serine/threonine-protein kinase
STE SLK SLK_HUMAN 8BEMB 2.6 Inactive DFGout‑BBAminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno AV9 Type1.5_Front 19 - 310 0 None None STE20-like serine/threonine-protein kinase
TYR KDR VGFR2_HUMAN 4ASEA 1.83 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai AV9 Type2 807 - 1169 0 None E990V Vascular endothelial growth factor receptor 2

Ligand: AV9 (Tivozanib, Fotivda)

Total number of chains: 5
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 5 100.0% 4ASEA
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
STE SLK SLK_HUMAN 8BEMD 2.6 Inactive DFGout‑BBAminus out-none none-out nonTYR APEdihe_aaioi APEdist_nnno AV9 Type1 19 - 310 0 None None STE20-like serine/threonine-protein kinase Homo sapiens
STE SLK SLK_HUMAN 8BEMG 2.6 Inactive DFGout‑BBAminus out-none none-out nonTYR APEdihe_aaioi APEdist_nnno AV9 Type1 19 - 309 0 None None STE20-like serine/threonine-protein kinase Homo sapiens
STE SLK SLK_HUMAN 8BEMA 2.6 Inactive DFGout‑BBAminus out-none none-out nonTYR APEdihe_aaioi APEdist_nnno AV9 Type1.5_Front 19 - 309 0 None None STE20-like serine/threonine-protein kinase Homo sapiens
STE SLK SLK_HUMAN 8BEMB 2.6 Inactive DFGout‑BBAminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno AV9 Type1.5_Front 19 - 310 0 None None STE20-like serine/threonine-protein kinase Homo sapiens
TYR KDR VGFR2_HUMAN 4ASEA 1.83 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai AV9 Type2 807 - 1169 0 None E990V Vascular endothelial growth factor receptor 2 Homo sapiens

Ligand: AV9 (Tivozanib, Fotivda)

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism