Ligand: L1X (Merestinib)

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 2 100.0% 7AAYA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR MERTK MERTK_HUMAN 7AAYA 1.87 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao L1X Type2 571 - 862 0 None None Tyrosine-protein kinase Mer
TYR MET MET_HUMAN 4EEVA 1.8 Inactive DFGout‑BBAminus in-out none-none TYR APEdihe_niiai APEdist_aaai L1X Type2 1045 - 1346 0 None None Hepatocyte growth factor receptor

Ligand: L1X (Merestinib)

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 2 100.0% 7AAYA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR MERTK MERTK_HUMAN 7AAYA 1.87 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao L1X Type2 571 - 862 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR MET MET_HUMAN 4EEVA 1.8 Inactive DFGout‑BBAminus in-out none-none TYR APEdihe_niiai APEdist_aaai L1X Type2 1045 - 1346 0 None None Hepatocyte growth factor receptor Homo sapiens

Ligand: L1X (Merestinib)

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism