9C1R

MET (Hepatocyte growth factor receptor)
Group: TYR
Uniprot: MET_HUMAN
Organism: Homo sapiens
Domain boundary: 1076 - 1339
Resolu: 1.59

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGout BBAminus in-out none-none A1ATS Type2 1047 - 1348 21
Representative sequence - Chain A
1056 1066 1076 1086
MQNTVHIDLS ALNPELVQAV QHVVIGPSSL IVHFNEVIGR
1096 1106 1116 1126
GHFGCVYHGT LLDNDGKKIH CAVKSLNRIT DIGEVSQFLT
1136 1146 1156 1166
EGIIMKDFSH PNVLSLLGIC LRSEGSPLVV LPYMKHGDLR
1176 1186 1196 1206
NFIRNETHNP TVKDLIGFGL QVAKGMKYLA SKKFVHRDLA
1216 1226 1236 1246
ARNCMLDEKF TVKVADFGla rnmydkeyys vhnktgaklP
1256 1266 1276 1286
VKWMALESLQ TQKFTTKSDV WSFGVLLWEL MTRGAPPYPD
1296 1306 1316 1326
VNTFDITVYL LQGRRLLQPE YCPDPLYEVM LKCWHPKAEM
1336 1346
RPSFSELVSR ISAIFSTFIG EHHHHHh
Lower-case residues are disordered in structure.
Mutations: D1228N
Phosphorylation: None