STE_SLK (STE20-like serine/threonine-protein kinase)

Total number of chains: 13
Active chains: 2
Uniprot: SLK_HUMAN
Kinase Domain Residues: 34 - 292
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 7 53.8% AF-Q9H2G2-K1A
DFGout BBAminus 4 30.8% 8BEMB
DFGinter None 2 15.4% 4USFB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q9H2G2-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 26 - 300 0 None None STE20-like serine/threonine-protein kinase
AF-Q9H2G2-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 26 - 300 0 None None STE20-like serine/threonine-protein kinase
2JFMA 2.85 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaiio APEdist_oooo No_ligand No_ligand 21 - 308 0 TPO183 None STE20-like serine/threonine-protein kinase
6HVDA 1.63 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oooo GUQ Type1 19 - 309 0 None None STE20-like serine/threonine-protein kinase
2J51A 2.1 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiio APEdist_oooo DKI Type1 21 - 308 0 None None STE20-like serine/threonine-protein kinase
2JFLA 2.2 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiio APEdist_oooo DKI Type1 21 - 308 0 TPO183,SEP189 None STE20-like serine/threonine-protein kinase
2UV2A 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiio APEdist_oooo GVD Type1 21 - 308 0 None K25T STE20-like serine/threonine-protein kinase
4USFA 1.75 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aanio APEdist_nnnn 6UI Type1 19 - 310 0 None None STE20-like serine/threonine-protein kinase
4USFB 1.75 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_nooi 6UI Type1 19 - 310 0 None None STE20-like serine/threonine-protein kinase
8BEMD 2.6 Inactive DFGout‑BBAminus out-none none-out nonTYR APEdihe_aaioi APEdist_nnno AV9 Type1 19 - 310 0 None None STE20-like serine/threonine-protein kinase
8BEMG 2.6 Inactive DFGout‑BBAminus out-none none-out nonTYR APEdihe_aaioi APEdist_nnno AV9 Type1 19 - 309 0 None None STE20-like serine/threonine-protein kinase
8BEMA 2.6 Inactive DFGout‑BBAminus out-none none-out nonTYR APEdihe_aaioi APEdist_nnno AV9 Type1.5_Front 19 - 309 0 None None STE20-like serine/threonine-protein kinase
8BEMB 2.6 Inactive DFGout‑BBAminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno AV9 Type1.5_Front 19 - 310 0 None None STE20-like serine/threonine-protein kinase

STE_SLK (STE20-like serine/threonine-protein kinase)

Total number of chains: 13
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 7 53.8% AF-Q9H2G2-K1A
DFGout BBAminus 4 30.8% 8BEMB
DFGinter None 2 15.4% 4USFB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
SLK_HUMAN AF-Q9H2G2-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 26 - 300 0 None None STE20-like serine/threonine-protein kinase Homo sapiens
SLK_HUMAN AF-Q9H2G2-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 26 - 300 0 None None STE20-like serine/threonine-protein kinase Homo sapiens
SLK_HUMAN 2JFMA 2.85 Inactive DFGin‑BLAminus in-none in-out nonTYR APEdihe_aaiio APEdist_oooo No_ligand No_ligand 21 - 308 0 TPO183 None STE20-like serine/threonine-protein kinase Homo sapiens
SLK_HUMAN 6HVDA 1.63 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaioi APEdist_oooo GUQ Type1 19 - 309 0 None None STE20-like serine/threonine-protein kinase Homo sapiens
SLK_HUMAN 2J51A 2.1 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiio APEdist_oooo DKI Type1 21 - 308 0 None None STE20-like serine/threonine-protein kinase Homo sapiens
SLK_HUMAN 2JFLA 2.2 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiio APEdist_oooo DKI Type1 21 - 308 0 TPO183,SEP189 None STE20-like serine/threonine-protein kinase Homo sapiens
SLK_HUMAN 2UV2A 2.3 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiio APEdist_oooo GVD Type1 21 - 308 0 None K25T STE20-like serine/threonine-protein kinase Homo sapiens
SLK_HUMAN 4USFA 1.75 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aanio APEdist_nnnn 6UI Type1 19 - 310 0 None None STE20-like serine/threonine-protein kinase Homo sapiens
SLK_HUMAN 4USFB 1.75 Inactive DFGinter‑None out-out out-out nonTYR APEdihe_aaiii APEdist_nooi 6UI Type1 19 - 310 0 None None STE20-like serine/threonine-protein kinase Homo sapiens
SLK_HUMAN 8BEMD 2.6 Inactive DFGout‑BBAminus out-none none-out nonTYR APEdihe_aaioi APEdist_nnno AV9 Type1 19 - 310 0 None None STE20-like serine/threonine-protein kinase Homo sapiens
SLK_HUMAN 8BEMG 2.6 Inactive DFGout‑BBAminus out-none none-out nonTYR APEdihe_aaioi APEdist_nnno AV9 Type1 19 - 309 0 None None STE20-like serine/threonine-protein kinase Homo sapiens
SLK_HUMAN 8BEMA 2.6 Inactive DFGout‑BBAminus out-none none-out nonTYR APEdihe_aaioi APEdist_nnno AV9 Type1.5_Front 19 - 309 0 None None STE20-like serine/threonine-protein kinase Homo sapiens
SLK_HUMAN 8BEMB 2.6 Inactive DFGout‑BBAminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno AV9 Type1.5_Front 19 - 310 0 None None STE20-like serine/threonine-protein kinase Homo sapiens

STE_SLK (STE20-like serine/threonine-protein kinase)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism