SLK (STE20-like serine/threonine-protein kinase)

Group: STE
Uniprot: SLK_HUMAN
Domain boundary: 34 - 292


Total number of chains: 12
Spatial Dihedral Chains Representative
DFGin BLAminus 6 AF-Q9H2G2-K1A
DFGinter None 2 4USFB
DFGout BBAminus 4 8BEMB
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
AF-Q9H2G2-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 26 - 300 None None 0
2JFMA 2.85 None DFGin BLAminus in-none in-out No_ligand No_ligand 21 - 308 None X183 0
6HVDA 1.63 Inactive DFGin BLAminus in-in in-out GUQ Type1 19 - 309 None None 6
2J51A 2.1 Inactive DFGin BLAminus in-out in-out DKI Type1 21 - 308 None None 0
2JFLA 2.2 Inactive DFGin BLAminus in-out in-out DKI Type1 21 - 308 None X183,X189 0
2UV2A 2.3 Inactive DFGin BLAminus in-in in-out GVD Type1 21 - 308 K25T None 0
4USFA 1.75 Inactive DFGinter None out-out out-none 6UI Type1 19 - 310 None None 13
4USFB 1.75 Inactive DFGinter None out-out out-in 6UI Type1 19 - 310 None None 9
8BEMD 2.6 Inactive DFGout BBAminus out-none none-out AV9 Type1 19 - 310 None None 13
8BEMG 2.6 Inactive DFGout BBAminus out-none none-out AV9 Type1 19 - 309 None None 14
8BEMA 2.6 Inactive DFGout BBAminus out-none none-out AV9 Type1.5_Front 19 - 309 None None 13
8BEMB 2.6 Inactive DFGout BBAminus out-out none-out AV9 Type1.5_Front 19 - 310 None None 13

SLK (STE20-like serine/threonine-protein kinase)

Group: STE
Total number of chains: 12
Spatial Dihedral Chains Representative
DFGin BLAminus 6 AF-Q9H2G2-K1A
DFGinter None 2 4USFB
DFGout BBAminus 4 8BEMB
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens SLK_HUMAN AF-Q9H2G2-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 26 - 300 None None 0
Homo sapiens SLK_HUMAN 2JFMA 2.85 None DFGin BLAminus in-none in-out No_ligand No_ligand 21 - 308 None X183 0
Homo sapiens SLK_HUMAN 6HVDA 1.63 Inactive DFGin BLAminus in-in in-out GUQ Type1 19 - 309 None None 6
Homo sapiens SLK_HUMAN 2J51A 2.1 Inactive DFGin BLAminus in-out in-out DKI Type1 21 - 308 None None 0
Homo sapiens SLK_HUMAN 2JFLA 2.2 Inactive DFGin BLAminus in-out in-out DKI Type1 21 - 308 None X183,X189 0
Homo sapiens SLK_HUMAN 2UV2A 2.3 Inactive DFGin BLAminus in-in in-out GVD Type1 21 - 308 K25T None 0
Homo sapiens SLK_HUMAN 4USFA 1.75 Inactive DFGinter None out-out out-none 6UI Type1 19 - 310 None None 13
Homo sapiens SLK_HUMAN 4USFB 1.75 Inactive DFGinter None out-out out-in 6UI Type1 19 - 310 None None 9
Homo sapiens SLK_HUMAN 8BEMD 2.6 Inactive DFGout BBAminus out-none none-out AV9 Type1 19 - 310 None None 13
Homo sapiens SLK_HUMAN 8BEMG 2.6 Inactive DFGout BBAminus out-none none-out AV9 Type1 19 - 309 None None 14
Homo sapiens SLK_HUMAN 8BEMA 2.6 Inactive DFGout BBAminus out-none none-out AV9 Type1.5_Front 19 - 309 None None 13
Homo sapiens SLK_HUMAN 8BEMB 2.6 Inactive DFGout BBAminus out-out none-out AV9 Type1.5_Front 19 - 310 None None 13

SLK (STE20-like serine/threonine-protein kinase)

No non-human structures known.