8UW2

AKT1 (RAC-alpha serine/threonine-protein kinase)
Group: AGC
Uniprot: AKT1_HUMAN
Organism: Homo sapiens
Domain boundary: 150 - 408
Resolu: 2.2

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGout BBAminus none-none out-out XOO Allosteric 4 - 437 7
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
        11         21         31         41 
sdVAIVKEGW LHKRGKYIKT WRPRYFLLKN DGTFIGYKER 
        51         61         71         81 
PQDvdqreAP LNNFSVAQCQ LMKTERPRPN TFIIRCLQWT 
        91        101        111        122 
TVIERTFHVE TPEEREEWTT AIQTVADGLK KQEEEEMDAS 
       138        148        158        168 
AEHTDMEvsl akpkhrVTMN EFEYLKLLGK GTFGKVILVK 
       178        188        198        208 
EKATGRYYAM KILKKEVIVa kdevahtlte nRVLQNSRHP 
       218        228        238        248 
FLTALKYSFQ THDRLCFVME YANGGELFFH LSRERVFSED 
       258        268        278        288 
RARFYGAEIV SALDYLHSEK NVVYRDLKLE NLMLDKDGHI 
       298        308        318        328 
KITDFGLCKE GikdgatmKT FCGTPEYLAP EVLEDNDYGR 
       338        348        358        368 
AVDWWGLGVV MYEMMCGRLP FYNQDHEKLF ELILMEEIRF 
       378        388        398        408 
PRTLGPEAKS LLSGLLKKDP KQRLGGGSED AKEIMQHRFF 
       418        428        438 
AGIVWQHVYE KKLSPPFKPQ VtsETDTRYf deeftaqm
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None