9GZH

PDGFRA (Platelet-derived growth factor receptor alpha)
Group: TYR
Uniprot: PGFRA_HUMAN
Organism: Homo sapiens
Domain boundary: 593 - 952
Resolu: 2.2

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGout BBAminus in-in out-in A1IRC Type2 583 - 958 0
Representative sequence - Chain A
556 566 576 586
gpgkqkprye irwrviesis pdgheyiyvd pmqlpyDSRW
596 606 616 626
EFPRDGLVLG RVLGSGAFGK VVEGTAYGLS RSQPVMKVAV
636 646 656 666
KMLKPTARSS EKQALMSELK IMTHLGPHLN IVNLLGACTK
676 686 696 778
SGPIYIIIEY CFYGDLVNYL HKNRDSFLsh kkksmldsev
788 798 808 818
knllsddnse GLTLLDLLSF TYQVARGMEF LASKNCVHRD
828 838 848 858
LAARNVLLAQ GKIVKICDFG LARDIMHDSN YVSKGSTFLP
868 878 888 898
VKWMAPESIF DNLYTTLSDV WSYGILLWEI FSLGGTPYPG
908 918 928 938
MMVDSTFYNK IKSGYRMAKP DHATSEVYEI MVKCWNSEPE
948 958 968
KRPSFYHLSE IVENLLPGQY kksyekihld flksd
Lower-case residues are disordered in structure.
Mutations: T674I
Phosphorylation: None