2XIR

KDR (Vascular endothelial growth factor receptor 2)
Group: TYR
Uniprot: VGFR2_HUMAN
Organism: Homo sapiens
Domain boundary: 834 - 1162
Resolu: 1.5

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGout BBAminus in-in out-in 00J Type1.5_Back 816 - 1168 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       815        825        835        845 
mdpdelplde HCERLPYDAS KWEFPRDRLK LGKPLGRGAF 
       855        865        875        885 
GQVIEADAFG IDKTATCRTV AVKMLKEGAT HSEHRALMSE 
       895        905        915        925 
LKILIHIGHH LNVVNLLGAC TKPGGPLMVI VEFCKFGNLS 
       935        995       1005       1015 
TYLRSKRNEF VPYkvapedl YKDFLTLEHL ICYSFQVAKG 
      1025       1035       1045       1055 
MEFLASRKCI HRDLAARNIL LSEKNVVKIC DFGLARDIYK 
      1065       1075       1085       1095 
DPDYVRKGDA RLPLKWMAPE TIFDRVYTIQ SDVWSFGVLL 
      1105       1115       1125       1135 
WEIFSLGASP YPGVKIDEEF CRRLKEGTRM RAPDYTTPEM 
      1145       1155       1165 
YQTMLDCWHG EPSQRPTFSE LVEHLGNLLQ ANAqqd
Lower-case residues are disordered in structure.
Mutations: E990V
Phosphorylation: None