Ligand: 37O

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 1 50.0% 4QQCA
DFGout BBAminus 1 50.0% 4QQ5A

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR FGFR4 FGFR4_HUMAN 4QQCA 2.4 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao 37O Type1.5_Back 445 - 750 0 None R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 4QQ5A 2.203 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao 37O Type1.5_Back 445 - 750 0 None V550L,R664E Fibroblast growth factor receptor 4

Ligand: 37O

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 2 50.0% 7D57A
DFGin BLAminus 1 25.0% 7D57B
DFGin BLAplus 1 25.0% 4QQCA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR SRC SRC_CHICK 7D57B 2.104 Inactive DFGin‑BLAminus in-out in-out TYR APEdihe_nniai APEdist_aaao 37O Type1.5_Back 257 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 7D57A 2.104 Inactive DFGout‑BBAminus out-out out-none TYR APEdihe_nnnai APEdist_aaan 37O Type1 258 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR FGFR4 FGFR4_HUMAN 4QQCA 2.4 Inactive DFGin‑BLAplus in-in none-out TYR APEdihe_nnoai APEdist_aaao 37O Type1.5_Back 445 - 750 0 None R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 4QQ5A 2.203 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao 37O Type1.5_Back 445 - 750 0 None V550L,R664E Fibroblast growth factor receptor 4 Homo sapiens

Ligand: 37O

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 7D57B
DFGout BBAminus 1 50.0% 7D57A

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR SRC SRC_CHICK 7D57B 2.104 Inactive DFGin‑BLAminus in-out in-out TYR APEdihe_nniai APEdist_aaao 37O Type1.5_Back 257 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 7D57A 2.104 Inactive DFGout‑BBAminus out-out out-none TYR APEdihe_nnnai APEdist_aaan 37O Type1 258 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus