Ligand: MDI

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 3 100.0% 8ANSA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR MET MET_HUMAN 8ANSA 2.01 Inactive DFGout‑BBAminus out-none in-none TYR APEdihe_nniai APEdist_aaai MDI Type1.5_Front 1052 - 1346 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8AN8A 2.394 Inactive DFGout‑BBAminus out-out in-none TYR APEdihe_nnnai APEdist_aaan MDI Type1.5_Front 1073 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8AN8B 2.394 Inactive DFGout‑BBAminus out-out in-none TYR APEdihe_nniai APEdist_aaai MDI Type1.5_Front 1058 - 1345 0 None None Hepatocyte growth factor receptor

Ligand: MDI

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 3 100.0% 8ANSA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR MET MET_HUMAN 8ANSA 2.01 Inactive DFGout‑BBAminus out-none in-none TYR APEdihe_nniai APEdist_aaai MDI Type1.5_Front 1052 - 1346 0 None D1228V Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8AN8A 2.394 Inactive DFGout‑BBAminus out-out in-none TYR APEdihe_nnnai APEdist_aaan MDI Type1.5_Front 1073 - 1345 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8AN8B 2.394 Inactive DFGout‑BBAminus out-out in-none TYR APEdihe_nniai APEdist_aaai MDI Type1.5_Front 1058 - 1345 0 None None Hepatocyte growth factor receptor Homo sapiens

Ligand: MDI

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism