Ligand: F88

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 3 100.0% 6GQPA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR KDR VGFR2_HUMAN 6GQPA 2.09 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_iiiai APEdist_aaao F88 Type2 821 - 1168 0 None None Vascular endothelial growth factor receptor 2
TYR KIT KIT_HUMAN 6GQKA 2.31 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_iiiai APEdist_aaao F88 Type2 567 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6GQKB 2.31 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_iiiai APEdist_aaao F88 Type2 572 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit

Ligand: F88

Total number of chains: 3
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 3 100.0% 6GQPA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR KDR VGFR2_HUMAN 6GQPA 2.09 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_iiiai APEdist_aaao F88 Type2 821 - 1168 0 None None Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KIT KIT_HUMAN 6GQKA 2.31 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_iiiai APEdist_aaao F88 Type2 567 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 6GQKB 2.31 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_iiiai APEdist_aaao F88 Type2 572 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit Homo sapiens

Ligand: F88

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism