Ligand: P30 (Quizartinib)

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 3 100.0% 4XUFB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR FLT3 FLT3_HUMAN 4XUFA 3.2 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai P30 Type2 600 - 947 0 None None Receptor-type tyrosine-protein kinase FLT3
TYR FLT3 FLT3_HUMAN 4XUFB 3.2 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai P30 Type2 600 - 946 0 None None Receptor-type tyrosine-protein kinase FLT3
TYR FLT3 FLT3_HUMAN 4RT7A 3.1 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai P30 Type2 599 - 950 0 None None Receptor-type tyrosine-protein kinase FLT3

Ligand: P30 (Quizartinib)

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 3 100.0% 4XUFB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR FLT3 FLT3_HUMAN 4XUFA 3.2 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai P30 Type2 600 - 947 0 None None Receptor-type tyrosine-protein kinase FLT3 Homo sapiens
TYR FLT3 FLT3_HUMAN 4XUFB 3.2 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai P30 Type2 600 - 946 0 None None Receptor-type tyrosine-protein kinase FLT3 Homo sapiens
TYR FLT3 FLT3_HUMAN 4RT7A 3.1 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai P30 Type2 599 - 950 0 None None Receptor-type tyrosine-protein kinase FLT3 Homo sapiens

Ligand: P30 (Quizartinib)

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism