Ligand: 585

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 3FQSA
DFGin None 1 50.0% 3PIYA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR BTK BTK_HUMAN 3PIYA 2.55 Inactive DFGin‑None out-out out-out TYR APEdihe_oiiai APEdist_aaao 585 Type1 391 - 658 0 None None Tyrosine-protein kinase BTK
TYR SYK KSYK_HUMAN 3FQSA 2.1 None DFGin‑BLAminus in-in in-none TYR APEdihe_niiai APEdist_aaai 585 Type1 363 - 635 0 None None Tyrosine-protein kinase SYK

Ligand: 585

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 3FQSA
DFGin None 1 50.0% 3PIYA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR BTK BTK_HUMAN 3PIYA 2.55 Inactive DFGin‑None out-out out-out TYR APEdihe_oiiai APEdist_aaao 585 Type1 391 - 658 0 None None Tyrosine-protein kinase BTK Homo sapiens
TYR SYK KSYK_HUMAN 3FQSA 2.1 None DFGin‑BLAminus in-in in-none TYR APEdihe_niiai APEdist_aaai 585 Type1 363 - 635 0 None None Tyrosine-protein kinase SYK Homo sapiens

Ligand: 585

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism