4G3D

MAP3K14 (Mitogen-activated protein kinase kinase kinase 14)
Group: STE
Uniprot: M3K14_HUMAN
Organism: Homo sapiens
Domain boundary: 399 - 653
Resolu: 2.9

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 332 - 672 0
B Active DFGin BLAminus in-in in-in No_ligand No_ligand 332 - 666 0
D Active DFGin BLAminus in-in in-in No_ligand No_ligand 338 - 657 13
E Active DFGin BLAminus in-in in-in No_ligand No_ligand 332 - 663 15
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain E
       315        325        335        345 
gsdspkplpg phlepsclsr gahekfSVEE YLVHALQGSV 
       355        365        375        385 
SSGQAHSLTS LAKTWAArgs rsrepspkte DNEGVLLTEK 
       395        405        415        425 
LKPVDYEYRE EVHWATHqlr lGRGSFGEVH RMEDKQTGFQ 
       435        445        455        465 
CAVKKVRLEV FRAEELMACA GLTSPRIVPL YGAVREGPWV 
       475        485        495        505 
NIFMELLEGG SLGQLVKEQG CLPEDRALYY LGQALEGLEY 
       515        525        535        545 
LHSRRILHGD VKADNVLLSS DGSHAALCDF GHAVCLQpdg 
       555        565        575        585 
lgkslltgdy iPGTeTHMAP EVVLGRSCDA KVDVWSSCCM 
       595        605        615        625 
MLHMLNGCHP wtqffrgplc lkiasepPPV REIPPSCAPL 
       635        645        655        665 
TAQAIQEGLR KEPIHRVSAA ELGGKVNRAL QQVGGLKSpw 
         - 
rgeykeprgn s
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None