Ligand: 37Q

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 4QPSC
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR JAK3-2 JAK3_HUMAN 4QPSA 1.8 None DFGin‑BLAminus in-in in-none TYR APEdihe_nnnai APEdist_aaan 37Q Type1 814 - 1100 0 None D949A,C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 4QPSC 1.8 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_nniai APEdist_aaao 37Q Type1 814 - 1102 0 None D949A,C1040S,C1048S Tyrosine-protein kinase JAK3

Ligand: 37Q

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 4QPSC
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR JAK3-2 JAK3_HUMAN 4QPSA 1.8 None DFGin‑BLAminus in-in in-none TYR APEdihe_nnnai APEdist_aaan 37Q Type1 814 - 1100 0 None D949A,C1040S,C1048S Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 4QPSC 1.8 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_nniai APEdist_aaao 37Q Type1 814 - 1102 0 None D949A,C1040S,C1048S Tyrosine-protein kinase JAK3 Homo sapiens

Ligand: 37Q

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism