4Z16

JAK3 (Tyrosine-protein kinase JAK3)
Group: TYR
Uniprot: JAK3_HUMAN
Organism: Homo sapiens
Domain boundary: 822 - 1111
Resolu: 2.9

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A None DFGin BLAminus in-in in-none 4LH Type1 814 - 1103 5
B Active DFGin BLAminus in-in in-in 4LH Type1 814 - 1103 0
C None DFGin BLAminus in-in in-none 4LH Type1 814 - 1103 5
D None DFGin BLAminus in-in in-none 4LH Type1 814 - 1103 5
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain D
       818        828        838        848 
gscqdPTIFE ERHLKYISQL GKGNFGSVEL CRYDPLGDNT 
       858        868        878        888 
GALVAVKQLQ HSGPDQQRDF QREIQILKAL HSDFIVKYRG 
       898        908        918        928 
VSYgpgrpEL RLVMEYLPSG CLRDFLQRHR ARLDASRLLL 
       938        948        958        968 
YSSQICKGME YLGSRRCVHR DLAARNILVE SEAHVKIADF 
       978        988        998       1008 
GLAKLLPLDK DYYVVRepgq sPIFWYAPES LSDNIFSRQS 
      1018       1028       1038       1048 
DVWSFGVVLY ELFTYCDKSC SPSAEFLRMM gcerdvpALC 
      1058       1068       1078       1088 
RLLELLEEGQ RLPAPPACPA EVHELMKLCW APSPQDRPSF 
      1098       1108       1118 
SALGPQLDML WSGSRgceth aftahpegkh hslsfs
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X980,X981