KinCore

CAMK_MAPKAPK3 (MAP kinase-activated protein kinase 3)

Total number of chains: 7

Active chains: 1

Uniprot: MAPK3_HUMAN

Kinase Domain Residues: 43 - 304

Spatial label	Dihedral label	Number of Chains	Percent	Representative
DFGin	BLAminus	7	100.0%	AF-Q16644-K3A

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PDB	Resolution	Activity	Spatial-Dihedral	Chelix-SaltBridge	ActLoopNT-ActLoopCT	APEtype	APEdihe	APEdist	Ligand	Ligand Type	Residues in structure	Unresolved residues in A-loop	Phosphorylation	Mutation	Protein
AF-Q16644-K3A	-1.0	Active	DFGin‑BLAminus	in-in	in-in	nonTYR	APEdihe_aaiii	APEdist_iiii	No_ligand	No_ligand	35 - 312	0	None	None	MAP kinase-activated protein kinase 3
AF-Q16644-K1A	-1.0	Inactive	DFGin‑BLAminus	in-in	in-out	nonTYR	APEdihe_aaiii	APEdist_oioi	No_ligand	No_ligand	35 - 312	0	None	None	MAP kinase-activated protein kinase 3
3R1NA	2.09	None	DFGin‑BLAminus	in-in	in-none	nonTYR	APEdihe_aannn	APEdist_nnnn	05B	Type1	33 - 348	0	None	None	MAP kinase-activated protein kinase 3
3SHEA	2.25	None	DFGin‑BLAminus	in-in	in-none	nonTYR	APEdihe_aannn	APEdist_nnnn	I85	Type1	33 - 348	0	None	None	MAP kinase-activated protein kinase 3
3FHRA	1.9	None	DFGin‑BLAminus	in-in	in-none	nonTYR	APEdihe_aannn	APEdist_nnnn	P4O	Type1	33 - 349	0	None	None	MAP kinase-activated protein kinase 3
3FXWA	2.0	None	DFGin‑BLAminus	in-in	in-none	nonTYR	APEdihe_aannn	APEdist_nnnn	F10	Type1	33 - 349	0	None	None	MAP kinase-activated protein kinase 3
7NRBA	1.9	None	DFGin‑BLAminus	in-in	in-none	nonTYR	APEdihe_aannn	APEdist_nnnn	P4O	Type1	33 - 349	0	None	None	MAP kinase-activated protein kinase 3

CAMK_MAPKAPK3 (MAP kinase-activated protein kinase 3)

Total number of chains: 7

Active chains: 1

Spatial label	Dihedral label	Number of Chains	Percent	Representative
DFGin	BLAminus	7	100.0%	AF-Q16644-K3A

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UniprotID	PDB	Resolution	Activity	Spatial-Dihedral	Chelix-SaltBridge	ActLoopNT-ActLoopCT	APEtype	APEdihe	APEdist	Ligand	Ligand Type	Residues in structure	Unresolved residues in A-loop	Phosphorylation	Mutation	Protein	Organism
MAPK3_HUMAN	AF-Q16644-K3A	-1.0	Active	DFGin‑BLAminus	in-in	in-in	nonTYR	APEdihe_aaiii	APEdist_iiii	No_ligand	No_ligand	35 - 312	0	None	None	MAP kinase-activated protein kinase 3	Homo sapiens
MAPK3_HUMAN	AF-Q16644-K1A	-1.0	Inactive	DFGin‑BLAminus	in-in	in-out	nonTYR	APEdihe_aaiii	APEdist_oioi	No_ligand	No_ligand	35 - 312	0	None	None	MAP kinase-activated protein kinase 3	Homo sapiens
MAPK3_HUMAN	3R1NA	2.09	None	DFGin‑BLAminus	in-in	in-none	nonTYR	APEdihe_aannn	APEdist_nnnn	05B	Type1	33 - 348	0	None	None	MAP kinase-activated protein kinase 3	Homo sapiens
MAPK3_HUMAN	3SHEA	2.25	None	DFGin‑BLAminus	in-in	in-none	nonTYR	APEdihe_aannn	APEdist_nnnn	I85	Type1	33 - 348	0	None	None	MAP kinase-activated protein kinase 3	Homo sapiens
MAPK3_HUMAN	3FHRA	1.9	None	DFGin‑BLAminus	in-in	in-none	nonTYR	APEdihe_aannn	APEdist_nnnn	P4O	Type1	33 - 349	0	None	None	MAP kinase-activated protein kinase 3	Homo sapiens
MAPK3_HUMAN	3FXWA	2.0	None	DFGin‑BLAminus	in-in	in-none	nonTYR	APEdihe_aannn	APEdist_nnnn	F10	Type1	33 - 349	0	None	None	MAP kinase-activated protein kinase 3	Homo sapiens
MAPK3_HUMAN	7NRBA	1.9	None	DFGin‑BLAminus	in-in	in-none	nonTYR	APEdihe_aannn	APEdist_nnnn	P4O	Type1	33 - 349	0	None	None	MAP kinase-activated protein kinase 3	Homo sapiens

CAMK_MAPKAPK3 (MAP kinase-activated protein kinase 3)

Total number of chains: 0

Active chains: 0

Spatial label	Dihedral label	Number of Chains	Percent	Representative

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UniprotID	PDB	Resolution	Activity	Spatial-Dihedral	Chelix-SaltBridge	ActLoopNT-ActLoopCT	APEtype	APEdihe	APEdist	Ligand	Ligand Type	Residues in structure	Unresolved residues in A-loop	Phosphorylation	Mutation	Protein	Organism