Ligand: VFC

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 3ZC6A

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR JAK3-2 JAK3_HUMAN 3ZC6A 2.42 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_noiai APEdist_aaai VFC Type1 814 - 1100 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 3ZC6B 2.42 None DFGin‑BLAminus in-in in-none TYR APEdihe_niiai APEdist_aaai VFC Type1 813 - 1100 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 3ZC6C 2.42 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_nniai APEdist_aaao VFC Type1 814 - 1100 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 3ZC6D 2.42 None DFGin‑BLAminus in-in in-none TYR APEdihe_nnnai APEdist_aaan VFC Type1 814 - 1100 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3

Ligand: VFC

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 3ZC6A

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR JAK3-2 JAK3_HUMAN 3ZC6A 2.42 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_noiai APEdist_aaai VFC Type1 814 - 1100 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 3ZC6B 2.42 None DFGin‑BLAminus in-in in-none TYR APEdihe_niiai APEdist_aaai VFC Type1 813 - 1100 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 3ZC6C 2.42 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_nniai APEdist_aaao VFC Type1 814 - 1100 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 3ZC6D 2.42 None DFGin‑BLAminus in-in in-none TYR APEdihe_nnnai APEdist_aaan VFC Type1 814 - 1100 0 PTR980,PTR981 C1040S,C1048S Tyrosine-protein kinase JAK3 Homo sapiens

Ligand: VFC

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism