8OMV

IKBKB (Inhibitor of nuclear factor kappa-B kinase subunit beta)
Group: OTHER
Uniprot: IKKB_HUMAN
Organism: Homo sapiens
Domain boundary: 15 - 308
Resolu: 4.16

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive None None in-in out-out No_ligand No_ligand 8 - 666 13
B Inactive DFGin BLBminus in-out out-out No_ligand No_ligand 8 - 664 9
C Inactive DFGin BLAminus in-out out-out No_ligand No_ligand 12 - 664 7
D Inactive DFGin BLAminus in-out out-out No_ligand No_ligand 6 - 665 8
E Inactive DFGinter None in-out out-out No_ligand No_ligand 9 - 643 3
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain E
         8         18         28         38 
ghmswspslt TQTCGAWEMK ErlgtggfGN VIRWHNQETG 
        48         58         68         78 
EQIAIKQCRQ ELSPRNRERW CLEIQIMRRL THPNVVAARD 
        88         98        108        118 
VPEGMQNLAP NDLPLLAMEY CQGGDLRKYL NQFENCCGLR 
       128        138        148        158 
EGAILTLLSD IASALRYLHE NRIIHRDLKP ENIVLQQGEQ 
       168        178        188        198 
RLIHKIIDLG YAKELdqgEL CTEFVGTLQY LAPELLEQQK 
       208        218        228        238 
YTVTVDYWSF GTLAFECITG FRPFLPNWQP VQWHSKVRQK 
       248        258        268        278 
SEVDIVVSED LNGTVKFSSS LPYPNNLNSV LAERLEKWLQ 
       288        298        308        318 
LMLMWHPRQR GTDPTYGPNG CFKALDDILN LKLVHILNMV 
       328        338        348        358 
TGTIHTYPVT EDESLQSLKA RIQQDTGIPE EDQELLQEAG 
       368        378        388        398 
LALIPDKPAT QCISdgklne ghTLDMDLVF LFDNSKITYE 
       408        418        428        438 
TQISPRPQPE SVSCILQEPK RNLAFFQLRK VWGQVWHSIQ 
       448        458        468        478 
TLKEDCNRLQ QGQRAAMMNL LRNNSCLSKM KNSMASMSQQ 
       488        498        508        518 
Lkakldffkt siqidlekys eqtefgitsd klllawreme 
       528        538        548        558 
qavelCGREN EVKLLVERMM ALQTDIVDLQ RSpmgrkqgG 
       568        578        588        598 
TLDDLEEQAR ELYRRLREKP RDQRTEGDSQ EMVRLLLQAI 
       608        618        628        638 
QSFEKKVRVI YTQLSKTVVC KQKALELLPK VEEVVSLMNE 
       648        658        668 
DEKTVvrlqe krqkelwnll kiacskvrgp v
Lower-case residues are disordered in structure.
Mutations: S177E,S181E
Phosphorylation: None