6W3C

ERN1 (Serine/threonine-protein kinase/endoribonuclease IRE1)
Group: OTHER
Uniprot: ERN1_HUMAN
Organism: Homo sapiens
Domain boundary: 569 - 832
Resolu: 2.3

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in No_ligand No_ligand 560 - 964 0
B Active DFGin BLAminus in-in in-in No_ligand No_ligand 560 - 963 0
C Active DFGin BLAminus in-in in-in No_ligand No_ligand 560 - 963 0
D Active DFGin BLAminus in-in in-in No_ligand No_ligand 560 - 963 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain D
       556        566        576        586 
gsspsleqdd gdeETSVVIV GKISFCPKDV LGHGAEGTIV 
       596        606        616        626 
YRGMFDNRDV AVKRILPECF SFADREVQLL RESDEHPNVI 
       636        646        656        666 
RYFCTEKDRQ FQYIAIELCA ATLQEYVEQK DFAHLGLEPI 
       676        686        696        706 
TLLQQTTSGL AHLHSLNIVH RDLKPHNILI SMPNAHGKIK 
       716        726        736        746 
AMISDFGLCK KLAVGRHSFS RRSGVPGTEG WIAPEMLSED 
       756        766        776        786 
CKENPTYTVD IFSAGCVFYY VISEGSHPFG KSLQRQANIL 
       796        806        816        826 
LGACSLDCLH PEKHEDVIAR ELIEKMIAMD PQKRPSAKHV 
       836        846        856        866 
LKHPFFWSLE KQLQFFQDVS DRIEKESLDG PIVKQLERGG 
       876        886        896        906 
RAVVKMDWRE NITVPLQTDL RKFRTYKGGS VRDLLRAMRN 
       916        926        936        946 
KKHHYRELPA EVRETLGSLP DDFVCYFTSR FPHLLAHTYR 
       956        966        976 
AMELCSHERL FQPYYFHepp epqppvtpda lgns
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X724,X726,X729