Ligand: Q8B

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6Z5AA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC CLK3 CLK3_HUMAN 6Z51A 1.92 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii Q8B Type1 134 - 484 0 None None Dual specificity protein kinase CLK3
OTHER HASPIN HASP_HUMAN 6Z5AA 1.55 Inactive DFGin‑BLAminus out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa Q8B Type1.5_Front 465 - 798 0 None None Serine/threonine-protein kinase haspin

Ligand: Q8B

Total number of chains: 2
Active chains: 1
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6Z5AA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC CLK3 CLK3_HUMAN 6Z51A 1.92 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii Q8B Type1 134 - 484 0 None None Dual specificity protein kinase CLK3 Homo sapiens
OTHER HASPIN HASP_HUMAN 6Z5AA 1.55 Inactive DFGin‑BLAminus out-out in-na noAPE APEdihe_aaaaa APEdist_aaaa Q8B Type1.5_Front 465 - 798 0 None None Serine/threonine-protein kinase haspin Homo sapiens

Ligand: Q8B

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism