PKMYT1 (Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase)

Group: OTHER
Uniprot: PMYT1_HUMAN
Domain boundary: 110 - 359


Total number of chains: 32
Spatial Dihedral Chains Representative
DFGin BLAminus 32 AF-Q99640-K1A
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
AF-Q99640-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 102 - 367 None None 0
3P1AA 1.7 Active DFGin BLAminus in-in in-in No_ligand No_ligand 76 - 362 None None 6
8ZTXA 1.7 Active DFGin BLAminus in-in in-in A1D83 Type1 75 - 361 None None 3
9LGVB 2.041 Active DFGin BLAminus in-in in-in A1EJV Type1 77 - 361 None None 6
8ZU2A 1.799 Active DFGin BLAminus in-in in-in A1D85 Type1 75 - 361 None None 5
8ZUDA 1.505 Active DFGin BLAminus in-in in-in A1D82 Type1 75 - 361 None None 3
8ZULA 1.8 Active DFGin BLAminus in-in in-in A1D84 Type1 75 - 361 None None 3
9LGLA 2.17 Active DFGin BLAminus in-in in-in A1EJW Type1 78 - 361 None None 7
9LGLB 2.17 Active DFGin BLAminus in-in in-in A1EJW Type1 75 - 361 None None 3
5VCVA 1.92 Active DFGin BLAminus in-in in-in 1N1 Type1 75 - 361 None X260 0
5VCWA 2.25 Active DFGin BLAminus in-in in-in 93J Type1 77 - 361 None None 0
5VCWB 2.25 Inactive DFGin BLAminus in-out in-in 93J Type1 77 - 361 None None 0
5VCXA 2.7 Active DFGin BLAminus in-in in-in H8H Type1 75 - 361 None None 0
5VCYA 1.56 Active DFGin BLAminus in-in in-in DB8 Type1 77 - 362 None None 0
5VCZA 1.5 Active DFGin BLAminus in-in in-in XZN Type1 78 - 361 None None 0
5VD0A 2.13 Active DFGin BLAminus in-in in-in 8X7 Type1 77 - 361 None None 0
5VD1A 1.7 Active DFGin BLAminus in-in in-in P48 Type1 77 - 361 None None 0
5VD3A 1.8 Active DFGin BLAminus in-in in-in H8H Type1 78 - 360 None None 0
8D6CA 2.2 Active DFGin BLAminus in-in in-in QGR Type1 78 - 362 None None 4
8D6CB 2.2 Active DFGin BLAminus in-in in-in QGR Type1 77 - 360 None None 3
8D6DB 2.35 Active DFGin BLAminus in-in in-in QGY Type1 77 - 361 None None 6
8D6EB 2.15 Active DFGin BLAminus in-in in-in QGI Type1 77 - 361 None None 0
8WJYA 1.88 Active DFGin BLAminus in-in in-in W9X Type1 76 - 361 None None 5
9LGVA 2.041 Active DFGin BLAminus in-in in-in A1EJV Type1.5_Back 77 - 361 None None 7
9LIDA 2.06 Active DFGin BLAminus in-in in-in A1EJX Type1.5_Back 77 - 361 None None 5
9LIDB 2.06 Active DFGin BLAminus in-in in-in A1EJX Type1.5_Back 77 - 361 None None 0
9LGNA 2.03 Active DFGin BLAminus in-in in-in A1EJU Type1.5_Back 77 - 361 None None 5
9LGNB 2.03 Active DFGin BLAminus in-in in-in A1EJU Type1.5_Back 77 - 361 None None 4
8D6DA 2.35 Active DFGin BLAminus in-in in-in QGY Type1.5_Back 78 - 361 None None 5
8D6EA 2.15 Active DFGin BLAminus in-in in-in QGI Type1.5_Back 77 - 361 None None 3
8D6FA 2.49 Active DFGin BLAminus in-in in-in QG5 Type1.5_Back 78 - 361 None None 6
8D6FB 2.49 Active DFGin BLAminus in-in in-in QG5 Type1.5_Back 76 - 361 None None 6

PKMYT1 (Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase)

Group: OTHER
Total number of chains: 32
Spatial Dihedral Chains Representative
DFGin BLAminus 32 AF-Q99640-K1A
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens PMYT1_HUMAN AF-Q99640-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 102 - 367 None None 0
Homo sapiens PMYT1_HUMAN 3P1AA 1.7 Active DFGin BLAminus in-in in-in No_ligand No_ligand 76 - 362 None None 6
Homo sapiens PMYT1_HUMAN 8ZTXA 1.7 Active DFGin BLAminus in-in in-in A1D83 Type1 75 - 361 None None 3
Homo sapiens PMYT1_HUMAN 9LGVB 2.041 Active DFGin BLAminus in-in in-in A1EJV Type1 77 - 361 None None 6
Homo sapiens PMYT1_HUMAN 8ZU2A 1.799 Active DFGin BLAminus in-in in-in A1D85 Type1 75 - 361 None None 5
Homo sapiens PMYT1_HUMAN 8ZUDA 1.505 Active DFGin BLAminus in-in in-in A1D82 Type1 75 - 361 None None 3
Homo sapiens PMYT1_HUMAN 8ZULA 1.8 Active DFGin BLAminus in-in in-in A1D84 Type1 75 - 361 None None 3
Homo sapiens PMYT1_HUMAN 9LGLA 2.17 Active DFGin BLAminus in-in in-in A1EJW Type1 78 - 361 None None 7
Homo sapiens PMYT1_HUMAN 9LGLB 2.17 Active DFGin BLAminus in-in in-in A1EJW Type1 75 - 361 None None 3
Homo sapiens PMYT1_HUMAN 5VCVA 1.92 Active DFGin BLAminus in-in in-in 1N1 Type1 75 - 361 None X260 0
Homo sapiens PMYT1_HUMAN 5VCWA 2.25 Active DFGin BLAminus in-in in-in 93J Type1 77 - 361 None None 0
Homo sapiens PMYT1_HUMAN 5VCWB 2.25 Inactive DFGin BLAminus in-out in-in 93J Type1 77 - 361 None None 0
Homo sapiens PMYT1_HUMAN 5VCXA 2.7 Active DFGin BLAminus in-in in-in H8H Type1 75 - 361 None None 0
Homo sapiens PMYT1_HUMAN 5VCYA 1.56 Active DFGin BLAminus in-in in-in DB8 Type1 77 - 362 None None 0
Homo sapiens PMYT1_HUMAN 5VCZA 1.5 Active DFGin BLAminus in-in in-in XZN Type1 78 - 361 None None 0
Homo sapiens PMYT1_HUMAN 5VD0A 2.13 Active DFGin BLAminus in-in in-in 8X7 Type1 77 - 361 None None 0
Homo sapiens PMYT1_HUMAN 5VD1A 1.7 Active DFGin BLAminus in-in in-in P48 Type1 77 - 361 None None 0
Homo sapiens PMYT1_HUMAN 5VD3A 1.8 Active DFGin BLAminus in-in in-in H8H Type1 78 - 360 None None 0
Homo sapiens PMYT1_HUMAN 8D6CA 2.2 Active DFGin BLAminus in-in in-in QGR Type1 78 - 362 None None 4
Homo sapiens PMYT1_HUMAN 8D6CB 2.2 Active DFGin BLAminus in-in in-in QGR Type1 77 - 360 None None 3
Homo sapiens PMYT1_HUMAN 8D6DB 2.35 Active DFGin BLAminus in-in in-in QGY Type1 77 - 361 None None 6
Homo sapiens PMYT1_HUMAN 8D6EB 2.15 Active DFGin BLAminus in-in in-in QGI Type1 77 - 361 None None 0
Homo sapiens PMYT1_HUMAN 8WJYA 1.88 Active DFGin BLAminus in-in in-in W9X Type1 76 - 361 None None 5
Homo sapiens PMYT1_HUMAN 9LGVA 2.041 Active DFGin BLAminus in-in in-in A1EJV Type1.5_Back 77 - 361 None None 7
Homo sapiens PMYT1_HUMAN 9LIDA 2.06 Active DFGin BLAminus in-in in-in A1EJX Type1.5_Back 77 - 361 None None 5
Homo sapiens PMYT1_HUMAN 9LIDB 2.06 Active DFGin BLAminus in-in in-in A1EJX Type1.5_Back 77 - 361 None None 0
Homo sapiens PMYT1_HUMAN 9LGNA 2.03 Active DFGin BLAminus in-in in-in A1EJU Type1.5_Back 77 - 361 None None 5
Homo sapiens PMYT1_HUMAN 9LGNB 2.03 Active DFGin BLAminus in-in in-in A1EJU Type1.5_Back 77 - 361 None None 4
Homo sapiens PMYT1_HUMAN 8D6DA 2.35 Active DFGin BLAminus in-in in-in QGY Type1.5_Back 78 - 361 None None 5
Homo sapiens PMYT1_HUMAN 8D6EA 2.15 Active DFGin BLAminus in-in in-in QGI Type1.5_Back 77 - 361 None None 3
Homo sapiens PMYT1_HUMAN 8D6FA 2.49 Active DFGin BLAminus in-in in-in QG5 Type1.5_Back 78 - 361 None None 6
Homo sapiens PMYT1_HUMAN 8D6FB 2.49 Active DFGin BLAminus in-in in-in QG5 Type1.5_Back 76 - 361 None None 6

PKMYT1 (Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase)

No non-human structures known.