6N3O

EIF2AK4 (eIF-2-alpha kinase GCN2)
Group: OTHER
Uniprot: E2AK4_HUMAN
Organism: Homo sapiens
Domain boundary: 590 - 1001
Resolu: 2.4

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A None DFGin BLAminus out-out out-none KA7 Type1.5_Back 584 - 1004 26
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       583        593        603        613 
ggssetqrqf SRYFIEFEEL QLLGKGAFGA VIKVQNKLDG 
       623        633        643        653 
CCYAVKRIPI NPASRQFRRI KGEVTLLSRL HHENIVRYYN 
       786        796        806        816 
AWIENgches epsvtteAVH YLYIQMEYCE ASTLRDTIDQ 
       826        836        846        856 
GLYRDTVRLW RLFREILDGL AYIHEKGMIH RNLKPVNIFL 
       866        876        886        896 
DSDDHVKIGD FGLATDHLAF Sadskqddqt gdliksdpsg 
       906        916        926        936 
hlegmvgEAL YVSPEvqgst ksaYNQKVDL FSLGIIFFEM 
       946        956        966        976 
SYHPMVTASE RIFVLNQLRD PTSPKFPEDF DDGEHAKQKS 
       986        996       1006 
VISWLLNHDP AKRPTATELL KSELLPPPqm eeselhe
Lower-case residues are disordered in structure.
Mutations: K807A,D848N,T899E,T904E
Phosphorylation: None