Ligand: XZN

Total number of chains: 3
Active chains: 0
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 5VCZA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
OTHER PKMYT1 PMYT1_HUMAN 5VCZA 1.5 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi XZN Type1 78 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
OTHER WEE1 WEE1_HUMAN 5VC4A 2.1 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiai APEdist_iooi XZN Type1 293 - 571 0 None None Wee1-like protein kinase
STE STK10 STK10_HUMAN 4BC6A 2.2 Inactive DFGin‑BLAminus in-out out-none nonTYR APEdihe_aannn APEdist_nnnn XZN Type1 24 - 316 0 None None Serine/threonine-protein kinase 10

Ligand: XZN

Total number of chains: 3
Active chains: 0
Total number of genes: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 5VCZA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
OTHER PKMYT1 PMYT1_HUMAN 5VCZA 1.5 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiai APEdist_iooi XZN Type1 78 - 361 0 None None Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Homo sapiens
OTHER WEE1 WEE1_HUMAN 5VC4A 2.1 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiai APEdist_iooi XZN Type1 293 - 571 0 None None Wee1-like protein kinase Homo sapiens
STE STK10 STK10_HUMAN 4BC6A 2.2 Inactive DFGin‑BLAminus in-out out-none nonTYR APEdihe_aannn APEdist_nnnn XZN Type1 24 - 316 0 None None Serine/threonine-protein kinase 10 Homo sapiens

Ligand: XZN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism