8UVL

ERN1 (Serine/threonine-protein kinase/endoribonuclease IRE1)
Group: OTHER
Uniprot: ERN1_HUMAN
Organism: Homo sapiens
Domain boundary: 569 - 832
Resolu: 2.43

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus out-out in-in XOE Type1.5_Front 562 - 964 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
         -        552        562        572 
mhhhhhhgen lyfqgsspsl eqddgdeetS VVIVGKISFC 
       582        592        602        612 
PKDVLGHGAE GTIVYRGMFD NRDVAVKRIL PECFSFADRE 
       622        632        642        652 
VQLLRESDEH PNVIRYFCTE KDRQFQYIAI ELCAATLQEY 
       662        672        682        692 
VEQKDFAHLG LEPITLLQQT TSGLAHLHSL NIVHRNLKPH 
       702        712        722        732 
NILISMPNAH GKIKAMISDF GLCKKLAVGR HSFSRRSGVP 
       742        752        762        772 
GTEGWIAPEM LSEDCKENPT YTVDIFSAGC VFYYVISEGS 
       782        792        802        812 
HPFGKSLQRQ ANILLGACSL DCLHPEKHED VIARELIEKM 
       822        832        842        852 
IAMDPQKRPS AKHVLKHPFF WSLEKQLQFF QDVSDRIEKE 
       862        872        882        892 
SLDGPIVKQL ERGGRAVVKM DWRENITVPL QTDLRKFRTY 
       902        912        922        932 
KGGSVRDLLR AMRNKKHHYR ELPAEVRETL GSLPDDFVCY 
       942        952        962        972 
FTSRFPHLLA HTYRAMELCS HERLFQPYYF HEppepqppv 

tpdalgns
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None