OTHER_CHUK (Inhibitor of nuclear factor kappa-B kinase subunit alpha)

Total number of chains: 20
Active chains: 2
Uniprot: IKKA_HUMAN
Kinase Domain Residues: 15 - 309
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 14 70.0% AF-O15111-K1A
None None 6 30.0% 5TQYA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-O15111-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 7 - 317 0 None None Inhibitor of nuclear factor kappa-B kinase subunit alpha
AF-O15111-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 7 - 317 0 None None Inhibitor of nuclear factor kappa-B kinase subunit alpha
5EBZA 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaooo APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
5EBZB 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
5EBZC 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoii APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
5EBZD 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaooo APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
5EBZE 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoii APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
5EBZF 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
5EBZG 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
5EBZH 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
5EBZI 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiio APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
5EBZJ 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
5EBZK 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoii APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
5EBZL 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
5TQWA 5.6 Inactive None‑None in-in none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 14 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
5TQWB 5.6 Inactive None‑None in-in none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 14 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
5TQXA 5.4 Inactive None‑None in-out none-none nonTYR APEdihe_aanii APEdist_nnnn No_ligand No_ligand 14 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
5TQXB 5.4 Inactive None‑None in-out none-none nonTYR APEdihe_aanii APEdist_nnnn No_ligand No_ligand 14 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
5TQYA 5.2 Inactive None‑None in-out none-none nonTYR APEdihe_aanii APEdist_nnnn No_ligand No_ligand 14 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha
5TQYB 5.2 Inactive None‑None in-out none-none nonTYR APEdihe_aanii APEdist_nnnn No_ligand No_ligand 14 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha

OTHER_CHUK (Inhibitor of nuclear factor kappa-B kinase subunit alpha)

Total number of chains: 20
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 14 70.0% AF-O15111-K1A
None None 6 30.0% 5TQYA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
IKKA_HUMAN AF-O15111-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 7 - 317 0 None None Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
IKKA_HUMAN AF-O15111-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 7 - 317 0 None None Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
IKKA_HUMAN 5EBZA 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaooo APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
IKKA_HUMAN 5EBZB 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
IKKA_HUMAN 5EBZC 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoii APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
IKKA_HUMAN 5EBZD 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaooo APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
IKKA_HUMAN 5EBZE 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoii APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
IKKA_HUMAN 5EBZF 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
IKKA_HUMAN 5EBZG 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
IKKA_HUMAN 5EBZH 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
IKKA_HUMAN 5EBZI 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiio APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
IKKA_HUMAN 5EBZJ 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
IKKA_HUMAN 5EBZK 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoii APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
IKKA_HUMAN 5EBZL 4.5 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaoio APEdist_iiio 5TL Type1 10 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
IKKA_HUMAN 5TQWA 5.6 Inactive None‑None in-in none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 14 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
IKKA_HUMAN 5TQWB 5.6 Inactive None‑None in-in none-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 14 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
IKKA_HUMAN 5TQXA 5.4 Inactive None‑None in-out none-none nonTYR APEdihe_aanii APEdist_nnnn No_ligand No_ligand 14 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
IKKA_HUMAN 5TQXB 5.4 Inactive None‑None in-out none-none nonTYR APEdihe_aanii APEdist_nnnn No_ligand No_ligand 14 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
IKKA_HUMAN 5TQYA 5.2 Inactive None‑None in-out none-none nonTYR APEdihe_aanii APEdist_nnnn No_ligand No_ligand 14 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens
IKKA_HUMAN 5TQYB 5.2 Inactive None‑None in-out none-none nonTYR APEdihe_aanii APEdist_nnnn No_ligand No_ligand 14 - 660 0 None S176E,S180E Inhibitor of nuclear factor kappa-B kinase subunit alpha Homo sapiens

OTHER_CHUK (Inhibitor of nuclear factor kappa-B kinase subunit alpha)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism