5EBZ

CHUK (Inhibitor of nuclear factor kappa-B kinase subunit alpha)
Group: OTHER
Uniprot: IKKA_HUMAN
Organism: Homo sapiens
Domain boundary: 15 - 309
Resolu: 4.5

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus in-out in-out 5TL Type1 10 - 660 0
B Inactive DFGin BLAminus in-out in-out 5TL Type1 10 - 660 0
C Inactive DFGin BLAminus in-out in-out 5TL Type1 10 - 660 0
D Inactive DFGin BLAminus in-out in-out 5TL Type1 10 - 660 0
E Inactive DFGin BLAminus in-out in-out 5TL Type1 10 - 660 0
F Inactive DFGin BLAminus in-out in-out 5TL Type1 10 - 660 0
G Inactive DFGin BLAminus in-out in-out 5TL Type1 10 - 660 0
H Inactive DFGin BLAminus in-out in-out 5TL Type1 10 - 660 0
I Inactive DFGin BLAminus in-out in-out 5TL Type1 10 - 660 0
J Inactive DFGin BLAminus in-out in-out 5TL Type1 10 - 660 0
K Inactive DFGin BLAminus in-out in-out 5TL Type1 10 - 660 0
L Inactive DFGin BLAminus in-out in-out 5TL Type1 10 - 660 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain L
        15         25         35         45 
DPEFGAGGPW EMRERLGTGG FGNVCLYQHR ELDLKIAIKS 
        55         65         75         85 
CRLELSTKNR ERWCHEIQIM KKLNHANVVK ACDVPEELNI 
        95        105        115        125 
LIHDVPLLAM EYCSGGDLRK LLNKPENCCG LKESQILSLL 
       135        145        155        165 
SDIGSGIRYL HENKIIHRDL KPENIVLQDV GGKIIHKIID 
       175        185        195        205 
LGYAKDVDQG ELCTEFVGTL QYLAPELFEN KPYTATVDYW 
       215        225        235        245 
SFGTMVFECI AGYRPFLHHL QPFTWHEKIK KKDPKCIFAC 
       255        265        275        285 
EEMSGEVRFS SHLPQPNSLC SLIVEPMENW LQLMLNWDPQ 
       295        305        315        325 
QRGGPVDLTL KQPRCFVLMD HILNLKIVHI LNMTSAKIIS 
       335        345        355        365 
FLLPPDESLH SLQSRIERET GINTGSQELL SETGISLDPR 
       375        385        395        405 
KPASQCVLDG VRGCDSYMVY LFDKSKTVYE GPFASRSLSD 
       415        425        435        445 
CVNYIVQDSK IQLPIIQLRK VWAEAVHYVS GLKEDYSRLF 
       455        465        475        485 
QGQRAAMLSL LRYNANLTKM KNTLISASQQ LKAKLEFFHK 
       495        505        515        525 
SIQLDLERYS EQMTYGISSE KMLKAWKEME EKAIHYAEVG 
       535        545        555        565 
VIGYLEDQIM SLHAEIMELQ KSPYGRRQGD LMESLEQRAI 
       575        585        595        605 
DLYKQLKHRP SDHSYSDSTE MVKIIVHTVQ SQDRVLKELF 
       615        625        635        645 
GHLSKLLGCK QKIIDLLPKV EVALSNIKEA DNTVMFMQGK 
       655 
RQKEIWHLLK IACTQ
Lower-case residues are disordered in structure.
Mutations: S176E,S180E
Phosphorylation: None