PDGFRA (Platelet-derived growth factor receptor alpha)

Group: TYR
Uniprot: PGFRA_HUMAN
Domain boundary: 593 - 952


Total number of chains: 12
Spatial Dihedral Chains Representative
DFGin BLAminus 3 AF-P16234-K1A
DFGin BLAplus 1 6JOIA
DFGout BBAminus 2 5GRNA
DFGout None 5 5K5XA
None None 1 6JOJA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
AF-P16234-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 585 - 960 None None 0
8PQHA 2.5 Active DFGin BLAminus in-in in-in 9JI Type1 555 - 971 T674I None 0
8PQIA 2.6 Active DFGin BLAminus in-in in-in 9OO Type1 567 - 969 T674I None 10
6JOIA 3.1 Inactive DFGin BLAplus in-out none-in 6T2 Type1 569 - 973 T674I None 15
5GRNA 1.77 Inactive DFGout BBAminus in-in out-in 748 Type2 583 - 958 None None 0
6JOLA 1.9 Inactive DFGout BBAminus in-in out-in STI Type2 583 - 957 None None 0
8PQKA 2.0 Inactive DFGout None in-in out-in No_ligand No_ligand 554 - 973 T674I None 0
6A32A 1.87 Inactive DFGout None in-in out-in No_ligand No_ligand 554 - 973 T674I None 0
8PQJA 1.82 Inactive DFGout None in-in out-in No_ligand No_ligand 553 - 973 None None 0
5K5XA 2.168 Inactive DFGout None in-in out-in No_ligand No_ligand 554 - 973 None None 0
6JOKA 3.8 Inactive DFGout None in-out out-in B49 Type1 556 - 973 None None 0
6JOJA 2.6 Inactive None None in-in out-in 6T2 Type1 554 - 973 None None 0

PDGFRA (Platelet-derived growth factor receptor alpha)

Group: TYR
Total number of chains: 12
Spatial Dihedral Chains Representative
DFGin BLAminus 3 AF-P16234-K1A
DFGin BLAplus 1 6JOIA
DFGout BBAminus 2 5GRNA
DFGout None 5 5K5XA
None None 1 6JOJA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens PGFRA_HUMAN AF-P16234-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 585 - 960 None None 0
Homo sapiens PGFRA_HUMAN 8PQHA 2.5 Active DFGin BLAminus in-in in-in 9JI Type1 555 - 971 T674I None 0
Homo sapiens PGFRA_HUMAN 8PQIA 2.6 Active DFGin BLAminus in-in in-in 9OO Type1 567 - 969 T674I None 10
Homo sapiens PGFRA_HUMAN 6JOIA 3.1 Inactive DFGin BLAplus in-out none-in 6T2 Type1 569 - 973 T674I None 15
Homo sapiens PGFRA_HUMAN 5GRNA 1.77 Inactive DFGout BBAminus in-in out-in 748 Type2 583 - 958 None None 0
Homo sapiens PGFRA_HUMAN 6JOLA 1.9 Inactive DFGout BBAminus in-in out-in STI Type2 583 - 957 None None 0
Homo sapiens PGFRA_HUMAN 8PQKA 2.0 Inactive DFGout None in-in out-in No_ligand No_ligand 554 - 973 T674I None 0
Homo sapiens PGFRA_HUMAN 6A32A 1.87 Inactive DFGout None in-in out-in No_ligand No_ligand 554 - 973 T674I None 0
Homo sapiens PGFRA_HUMAN 8PQJA 1.82 Inactive DFGout None in-in out-in No_ligand No_ligand 553 - 973 None None 0
Homo sapiens PGFRA_HUMAN 5K5XA 2.168 Inactive DFGout None in-in out-in No_ligand No_ligand 554 - 973 None None 0
Homo sapiens PGFRA_HUMAN 6JOKA 3.8 Inactive DFGout None in-out out-in B49 Type1 556 - 973 None None 0
Homo sapiens PGFRA_HUMAN 6JOJA 2.6 Inactive None None in-in out-in 6T2 Type1 554 - 973 None None 0

PDGFRA (Platelet-derived growth factor receptor alpha)

No non-human structures known.