5CEN

MAP3K12 (Mitogen-activated protein kinase kinase kinase 12)
Group: TKL
Uniprot: M3K12_HUMAN
Organism: Homo sapiens
Domain boundary: 125 - 366
Resolu: 1.7

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLBminus out-out out-out No_ligand No_ligand 117 - 397 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       121        131        141        151 
mgsedLWEVP FEEILDLQWV GSGAQGAVFL GRFHGEEVAV 
       161        171        181        191 
KKVRDLKETD IKHLRKLKHP NIITFKGVCT QAPCYCILME 
       201        211        221        231 
FCAQGQLYEV LRAGRPVTPS LLVDWSMGIA GGMNYLHLHK 
       241        251        261        271 
IIHRDLKSPN MLITYDDVVK ISDFGTSKEL SDKSTKMSFA 
       281        291        301        311 
GTVAWMAPEV IRNEPVSEKV DIWSFGVVLW ELLTGEIPYK 
       321        331        341        351 
DVDSSAIIWG VGSNSLHLPV PSSCPDGFKI LLRQCWNSKP 
       361        371        381        391 
RNRPSFRQIL LHLDIASADV LSTPQETYFK SQAEWREEVK 
       401          - 
LHFEKIkseg tgnshhhhhh
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None