| Spatial | Dihedral | Chains | Representative |
|---|---|---|---|
| DFGin | BLAminus | 1 | AF-P27448-K1A |
| DFGin | BLBminus | 1 | 7P1LA |
| None | None | 5 | 3FE3A |
| PDB | Resolution | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Mutation | Phosphorylation | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AF-P27448-K1A | -1.0 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 48 - 315 | None | None | 0 |
| 7P1LA | 1.95 | Inactive | DFGin | BLBminus | out-out | out-none | V5E | Type1 | 50 - 365 | None | None | 9 |
| 2QNJA | 2.7 | Inactive | None | None | in-out | out-out | No_ligand | No_ligand | 44 - 366 | None | None | 5 |
| 2QNJB | 2.7 | Inactive | None | None | out-out | out-out | No_ligand | No_ligand | 44 - 367 | None | None | 3 |
| 3FE3A | 1.9 | Inactive | None | None | out-out | out-out | No_ligand | No_ligand | 50 - 366 | T211A,S215A | None | 0 |
| 3FE3B | 1.9 | Inactive | None | None | out-out | out-out | No_ligand | No_ligand | 50 - 366 | T211A,S215A | None | 0 |
| 7P1LB | 1.95 | Inactive | None | None | out-out | out-none | V5E | Type1 | 50 - 365 | None | None | 9 |
| Spatial | Dihedral | Chains | Representative |
|---|---|---|---|
| DFGin | BLAminus | 1 | AF-P27448-K1A |
| DFGin | BLBminus | 1 | 7P1LA |
| None | None | 5 | 3FE3A |
| Organism | UniprotID | PDB | Resolution | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Mutation | Phosphorylation | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Homo sapiens | MARK3_HUMAN | AF-P27448-K1A | -1.0 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 48 - 315 | None | None | 0 |
| Homo sapiens | MARK3_HUMAN | 7P1LA | 1.95 | Inactive | DFGin | BLBminus | out-out | out-none | V5E | Type1 | 50 - 365 | None | None | 9 |
| Homo sapiens | MARK3_HUMAN | 2QNJA | 2.7 | Inactive | None | None | in-out | out-out | No_ligand | No_ligand | 44 - 366 | None | None | 5 |
| Homo sapiens | MARK3_HUMAN | 2QNJB | 2.7 | Inactive | None | None | out-out | out-out | No_ligand | No_ligand | 44 - 367 | None | None | 3 |
| Homo sapiens | MARK3_HUMAN | 3FE3A | 1.9 | Inactive | None | None | out-out | out-out | No_ligand | No_ligand | 50 - 366 | T211A,S215A | None | 0 |
| Homo sapiens | MARK3_HUMAN | 3FE3B | 1.9 | Inactive | None | None | out-out | out-out | No_ligand | No_ligand | 50 - 366 | T211A,S215A | None | 0 |
| Homo sapiens | MARK3_HUMAN | 7P1LB | 1.95 | Inactive | None | None | out-out | out-none | V5E | Type1 | 50 - 365 | None | None | 9 |