IKBKB (Inhibitor of nuclear factor kappa-B kinase subunit beta)

Group: OTHER
Uniprot: IKKB_HUMAN
Domain boundary: 15 - 308


Total number of chains: 9
Spatial Dihedral Chains Representative
DFGin BLAminus 7 AF-O14920-K1A
DFGin None 2 4E3CA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
AF-O14920-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 7 - 316 None None 0
4E3CB 3.98 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand 16 - 665 S177E,S181E None 0
4E3CC 3.98 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand 16 - 665 S177E,S181E None 0
4E3CD 3.98 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand 16 - 665 S177E,S181E None 0
4E3CF 3.98 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand 16 - 665 S177E,S181E None 0
4KIKA 2.83 None DFGin BLAminus in-in none-out KSA Type1 9 - 663 None X257 10
4KIKB 2.83 Active DFGin BLAminus in-in in-in KSA Type1 2 - 663 None X177,X181 3
4E3CA 3.98 Inactive DFGin None in-in in-out No_ligand No_ligand 16 - 665 S177E,S181E None 0
4E3CE 3.98 Inactive DFGin None in-in in-out No_ligand No_ligand 16 - 665 S177E,S181E None 0

IKBKB (Inhibitor of nuclear factor kappa-B kinase subunit beta)

Group: OTHER
Total number of chains: 9
Spatial Dihedral Chains Representative
DFGin BLAminus 7 AF-O14920-K1A
DFGin None 2 4E3CA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens IKKB_HUMAN AF-O14920-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 7 - 316 None None 0
Homo sapiens IKKB_HUMAN 4E3CB 3.98 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand 16 - 665 S177E,S181E None 0
Homo sapiens IKKB_HUMAN 4E3CC 3.98 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand 16 - 665 S177E,S181E None 0
Homo sapiens IKKB_HUMAN 4E3CD 3.98 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand 16 - 665 S177E,S181E None 0
Homo sapiens IKKB_HUMAN 4E3CF 3.98 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand 16 - 665 S177E,S181E None 0
Homo sapiens IKKB_HUMAN 4KIKA 2.83 None DFGin BLAminus in-in none-out KSA Type1 9 - 663 None X257 10
Homo sapiens IKKB_HUMAN 4KIKB 2.83 Active DFGin BLAminus in-in in-in KSA Type1 2 - 663 None X177,X181 3
Homo sapiens IKKB_HUMAN 4E3CA 3.98 Inactive DFGin None in-in in-out No_ligand No_ligand 16 - 665 S177E,S181E None 0
Homo sapiens IKKB_HUMAN 4E3CE 3.98 Inactive DFGin None in-in in-out No_ligand No_ligand 16 - 665 S177E,S181E None 0

IKBKB (Inhibitor of nuclear factor kappa-B kinase subunit beta)

No non-human structures known.