CDKL2 (Cyclin-dependent kinase-like 2)

Group: CMGC

Uniprot: CDKL2_HUMAN

Domain boundary: 4 - 287

Total number of chains: 4

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	1	AF-Q92772-K1A
DFGin	BLAplus	1	4BBMB
DFGin	BLBminus	1	4AAAA
DFGin	None	1	4BBMA

Database table as tsv

PDB	Resolution	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Mutation	Phosphorylation	Unresolved residues in A-loop
AF-Q92772-K1A	-1.0	Active	DFGin	BLAminus	in-in	in-in	No_ligand	No_ligand	1 - 295	None	None	0
4BBMB	2.0	Inactive	DFGin	BLAplus	out-none	out-out	TC0	Type1	1 - 308	T159D,Y161E	None	0
4AAAA	1.53	Inactive	DFGin	BLBminus	out-none	none-out	DKI	Type1	1 - 302	T159D,Y161E	None	12
4BBMA	2.0	Inactive	DFGin	None	out-none	out-out	TC0	Type1	1 - 308	T159D,Y161E	None	0

CDKL2 (Cyclin-dependent kinase-like 2)

Group: CMGC

Total number of chains: 4

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	1	AF-Q92772-K1A
DFGin	BLAplus	1	4BBMB
DFGin	BLBminus	1	4AAAA
DFGin	None	1	4BBMA

Database table as tsv

Organism	UniprotID	PDB	Resolution	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Mutation	Phosphorylation	Unresolved residues in A-loop
Homo sapiens	CDKL2_HUMAN	AF-Q92772-K1A	-1.0	Active	DFGin	BLAminus	in-in	in-in	No_ligand	No_ligand	1 - 295	None	None	0
Homo sapiens	CDKL2_HUMAN	4BBMB	2.0	Inactive	DFGin	BLAplus	out-none	out-out	TC0	Type1	1 - 308	T159D,Y161E	None	0
Homo sapiens	CDKL2_HUMAN	4AAAA	1.53	Inactive	DFGin	BLBminus	out-none	none-out	DKI	Type1	1 - 302	T159D,Y161E	None	12
Homo sapiens	CDKL2_HUMAN	4BBMA	2.0	Inactive	DFGin	None	out-none	out-out	TC0	Type1	1 - 308	T159D,Y161E	None	0

CDKL2 (Cyclin-dependent kinase-like 2)

No non-human structures known.