4CQE

BRAF (Serine/threonine-protein kinase B-raf)
Group: TKL
Uniprot: BRAF_HUMAN
Organism: Homo sapiens
Domain boundary: 457 - 716
Resolu: 2.3

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAplus out-out none-out CQE Type1.5_Back 449 - 720 18
B Inactive DFGin BLBminus in-out none-out CQE Type1.5_Back 448 - 720 18
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       455        465        475        485 
gpDDWEIPDG QITVGQRIGS gsfGTVYKGK WHGDVAVKML 
       495        505        515        525 
NVTAPTPQQL QAFKNEVGVL RKTRHVNILL FMGYSTKPQL 
       535        545        555        565 
AIVTQWCEGS SLYHHLHASE TKFEMKKLID IARQTARGMD 
       575        585        595        605 
YLHAKSIIHR DLKSNNIFLH EDNTVKIGDF Glateksrws 
       615        625        635        645 
gshqfeqlsG SILWMAPEVI RmqdsNPYSF QSDVYAFGIV 
       655        665        675        685 
LYELMTGQLP YSNINNRDQI IEMVGRGSLS PDLSKVRSNC 
       695        705        715 
PKRMKRLMAE CLKKKRDERP SFPRILAEIE ELARElsg
Lower-case residues are disordered in structure.
Mutations: I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G
Phosphorylation: None