| Chain id | Activity_label | Spatial_label | Dihedral_label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|
| A | Inactive | DFGin | BLBminus | out-out | out-out | CPS | Type1 | 25 - 315 | 0 |
| B | Inactive | DFGin | BLBminus | out-out | out-out | CPS | Type1 | 25 - 313 | 0 |
| C | Inactive | DFGin | BLBminus | out-out | out-out | CPS CPS | Type1 Allosteric | 28 - 313 | 0 |
| D | Inactive | DFGin | BLBminus | out-out | out-out | CPS CPS CPS | Type1 Allosteric Allosteric | 25 - 324 | 0 |
Representative sequence - Chain D
28 38 48 58
PGIHSGRTRV GKYELGRTLG EGTFAKVKFA RNVENGDNVA
68 78 88 98
IKVIDKEKVL KNKMIAQIKR EISTMKLIKH PNVIRMFEVM
108 118 128 138
ASKTKIYFVL EFVTGGELFD KISSNGRLKE DEARKYFQQL
148 158 168 178
INAVDYCHSR GVYHRDLKPE NLLLDANGAL KVSDFGLSAL
188 198 208 218
PQQVREDGLL HTTCGTPNYV APEVINNKGY DGAKADLWSC
228 238 248 258
GVILFVLMAG YLPFEDSNLT SLYKKIFKAE FTCPPWFSAS
268 278 288 298
AKKLIKRILD PNPATRITFA EVIENEWFKK GYKAPKFENA
308 318 328 338
DVSLDDVDAI FDDSgeskNL VVERREeglk tpvtmnafel
348 358 368 378
istsqglnlg slfekqmglv krktrftsks saneivtkie
388 398 408 418
aaaapmgfdv ktnnykmklt geksgrkgql avatevfqva
428 438 448 458
pslymvemrk sggdtlefhk fyknlttglk divwktidee
468 478
keegtdgggt ngamanrtia kqst