6LK6

MLKL (Mixed lineage kinase domain-like protein)
Pseudokinase
Group: OTHER
Uniprot: MLKL_HUMAN
Organism: Homo sapiens
Domain boundary: 201 - 468
Resolu: 2.41

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLBminus in-in out-out No_ligand No_ligand 192 - 470 14
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       188        198        208        218 
ylppkcmqei pqeQIKEIKK EQLSGSPWIL LRENEVSTLY 
       228        238        248        258 
KGEYHRAPVA IKVFKKLQAG SIAIVRQTFN KEIKTMKKFE 
       268        278        288        298 
SPNILRIFGI CIDETVTPPQ FSIVMEYCEL GTLRELLDRE 
       308        318        328        338 
KDLTLGKRMV LVLGAARGLY RLHHSEAPEL HGKIRSSNFL 
       348        358        368        378 
VTQGYQVKLA GFELRKtqaa mslgttrekt DRVKSTAYLS 
       388        398        408        418 
PQELEDVFYQ YDVKSEIYSF GIVLWEIATG DIPFQGCNSE 
       428        438        448        458 
KIRKLVAVKR QQEPLGEDCP SELREIIDEC RAHDPSVRPS 
       468 
VDEILKKLST FSk
Lower-case residues are disordered in structure.
Mutations: T357A,S358A
Phosphorylation: None