Protein kinases in complex with SB2

Total number of genes: 3
Total number of chains: 8
Spatial Dihedral Chains Representative
DFGin BLAminus 1 1PMEA
DFGin BLBminus 2 1A9UA
DFGin BLBplus 2 5AR4B
DFGin None 1 3OBGA
DFGinter None 2 3ZS5A
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 1PMEA 2.0 Active DFGin BLAminus out-in in-in SB2 Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1A9UA 2.5 Inactive DFGin BLBminus in-in out-out SB2 Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3MPAA 2.1 Inactive DFGin BLBminus in-in none-none SB2 Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3OBGA 2.8 Inactive DFGin None in-in none-none SB2 Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3GCPA 2.25 Inactive DFGinter None in-in none-none SB2 Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3ZS5A 1.6 Inactive DFGinter None in-in none-out SB2 Type1
TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5AR4A 2.7 Inactive DFGin BLBplus in-in none-none SB2 Type1
TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5AR4B 2.7 Inactive DFGin BLBplus in-in none-out SB2 Type1

Protein kinases in complex with SB2

Total number of genes: 4
Total number of chains: 12
Spatial Dihedral Chains Representative
DFGin BLAminus 1 1PMEA
DFGin BLAplus 1 3UIBA
DFGin BLBminus 2 1A9UA
DFGin BLBplus 3 8ACMAAA
DFGin None 3 8ACOAAA
DFGinter None 2 3ZS5A
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 1PMEA 2.0 Active DFGin BLAminus out-in in-in SB2 Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1A9UA 2.5 Inactive DFGin BLBminus in-in out-out SB2 Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3MPAA 2.1 Inactive DFGin BLBminus in-in none-none SB2 Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3OBGA 2.8 Inactive DFGin None in-in none-none SB2 Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3GCPA 2.25 Inactive DFGinter None in-in none-none SB2 Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3ZS5A 1.6 Inactive DFGinter None in-in none-out SB2 Type1
Homo sapiens TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5AR4A 2.7 Inactive DFGin BLBplus in-in none-none SB2 Type1
Homo sapiens TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5AR4B 2.7 Inactive DFGin BLBplus in-in none-out SB2 Type1
Leishmania major CMGC MPK10 Q4QHJ8_LEIMA Putative mitogen-activated protein kinase 3UIBA 2.65 Inactive DFGin BLAplus in-in none-out SB2 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 8ACMAAA 2.14 Inactive DFGin BLBplus in-in none-none SB2 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 8ACOAAA 2.65 Inactive DFGin None in-in none-none SB2 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 2EWAA 2.1 Inactive DFGin None in-in none-none SB2 Type1

Protein kinases in complex with SB2

Total number of genes: 2
Total number of chains: 4
Spatial Dihedral Chains Representative
DFGin BLAplus 1 3UIBA
DFGin BLBplus 1 8ACMAAA
DFGin None 2 8ACOAAA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Leishmania major CMGC MPK10 Q4QHJ8_LEIMA Putative mitogen-activated protein kinase 3UIBA 2.65 Inactive DFGin BLAplus in-in none-out SB2 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 8ACMAAA 2.14 Inactive DFGin BLBplus in-in none-none SB2 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 8ACOAAA 2.65 Inactive DFGin None in-in none-none SB2 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 2EWAA 2.1 Inactive DFGin None in-in none-none SB2 Type1