WNK3 (Serine/threonine-protein kinase WNK3)

Group: OTHER
Uniprot: WNK3_HUMAN
Domain boundary: 146 - 405


Total number of chains: 14
Spatial Dihedral Chains Representative
DFGin BLAminus 7 AF-Q9BYP7-K1A
DFGin BLBminus 4 5O1VA
DFGin BLBtrans 1 5O2BA
DFGin None 2 5O23A
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
AF-Q9BYP7-K1A -1.0 Active DFGin BLAminus out-none in-in No_ligand No_ligand 138 - 413 None None 0
5O21A 2.06 Inactive DFGin BLAminus out-none out-out No_ligand No_ligand 135 - 407 None X304 0
5O21B 2.06 Inactive DFGin BLAminus out-none out-out No_ligand No_ligand 135 - 408 None X304 0
8EDHC 3.111 None DFGin BLAminus out-none out-none No_ligand No_ligand 136 - 407 S308A None 11
5O26A 2.379 Active DFGin BLAminus out-none in-in ANP Type1 135 - 414 None X304,X308 0
5O26B 2.379 Active DFGin BLAminus out-none in-in ANP Type1 136 - 413 None X304,X308 0
8EDHA 3.111 None DFGin BLAminus out-none out-none WGK Type1 137 - 406 S308A None 12
5O1VA 1.723 Inactive DFGin BLBminus out-none out-out No_ligand No_ligand 134 - 412 None X304 0
5O1VB 1.723 Inactive DFGin BLBminus out-none out-out No_ligand No_ligand 134 - 410 None X304 6
5O2CA 2.4 Inactive DFGin BLBminus out-none out-in No_ligand No_ligand 129 - 496 None None 0
5O2BB 2.038 Inactive DFGin BLBminus out-none out-none KS1 Type1 135 - 406 None None 10
5O2BA 2.038 Inactive DFGin BLBtrans out-none out-out KS1 Type1 132 - 414 None None 8
5O23A 2.25 Inactive DFGin None out-none out-out No_ligand No_ligand 136 - 405 None X304 0
5O23B 2.25 Inactive DFGin None out-none out-out No_ligand No_ligand 132 - 408 None X304 0

WNK3 (Serine/threonine-protein kinase WNK3)

Group: OTHER
Total number of chains: 14
Spatial Dihedral Chains Representative
DFGin BLAminus 7 AF-Q9BYP7-K1A
DFGin BLBminus 4 5O1VA
DFGin BLBtrans 1 5O2BA
DFGin None 2 5O23A
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens WNK3_HUMAN AF-Q9BYP7-K1A -1.0 Active DFGin BLAminus out-none in-in No_ligand No_ligand 138 - 413 None None 0
Homo sapiens WNK3_HUMAN 5O21A 2.06 Inactive DFGin BLAminus out-none out-out No_ligand No_ligand 135 - 407 None X304 0
Homo sapiens WNK3_HUMAN 5O21B 2.06 Inactive DFGin BLAminus out-none out-out No_ligand No_ligand 135 - 408 None X304 0
Homo sapiens WNK3_HUMAN 8EDHC 3.111 None DFGin BLAminus out-none out-none No_ligand No_ligand 136 - 407 S308A None 11
Homo sapiens WNK3_HUMAN 5O26A 2.379 Active DFGin BLAminus out-none in-in ANP Type1 135 - 414 None X304,X308 0
Homo sapiens WNK3_HUMAN 5O26B 2.379 Active DFGin BLAminus out-none in-in ANP Type1 136 - 413 None X304,X308 0
Homo sapiens WNK3_HUMAN 8EDHA 3.111 None DFGin BLAminus out-none out-none WGK Type1 137 - 406 S308A None 12
Homo sapiens WNK3_HUMAN 5O1VA 1.723 Inactive DFGin BLBminus out-none out-out No_ligand No_ligand 134 - 412 None X304 0
Homo sapiens WNK3_HUMAN 5O1VB 1.723 Inactive DFGin BLBminus out-none out-out No_ligand No_ligand 134 - 410 None X304 6
Homo sapiens WNK3_HUMAN 5O2CA 2.4 Inactive DFGin BLBminus out-none out-in No_ligand No_ligand 129 - 496 None None 0
Homo sapiens WNK3_HUMAN 5O2BB 2.038 Inactive DFGin BLBminus out-none out-none KS1 Type1 135 - 406 None None 10
Homo sapiens WNK3_HUMAN 5O2BA 2.038 Inactive DFGin BLBtrans out-none out-out KS1 Type1 132 - 414 None None 8
Homo sapiens WNK3_HUMAN 5O23A 2.25 Inactive DFGin None out-none out-out No_ligand No_ligand 136 - 405 None X304 0
Homo sapiens WNK3_HUMAN 5O23B 2.25 Inactive DFGin None out-none out-out No_ligand No_ligand 132 - 408 None X304 0

WNK3 (Serine/threonine-protein kinase WNK3)

No non-human structures known.