7S26

ROCK1 (Rho-associated protein kinase 1)
Group: AGC
Uniprot: ROCK1_HUMAN
Organism: Homo sapiens
Domain boundary: 76 - 338
Resolu: 2.744

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A None DFGin BLAminus in-in in-none 86K Type1 6 - 401 6
B None DFGin BLAminus in-in none-none 86K Type1 6 - 402 19
C Inactive DFGin BLBminus in-in none-none 86K Type1 8 - 402 18
D None DFGin BLAminus in-in in-none No_ligand No_ligand 6 - 399 23
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain D
        14         24         34         44 
aSFETRFEKM DNLLRDPKSE VNSDCLLDGL DALVYDLDFP 
        54         64         74         84 
ALRKNKNIDN FLSRYKDTIN KIRDLRMKAE DYEVVKVIGR 
        94        104        114        124 
GAFGEVQLVR HKSTRKVYAM KLLSKFEMIK RSDSAFFWEE 
       134        144        154        164 
RDIMAFANSP WVVQLFYAFQ DDRYLYMVME YMPGGDLVNL 
       174        184        194        204 
MSNYDVPEKW ARFYTAEVVL ALDAIHSMGF IHRDVKPDNM 
       214        224        234        244 
LLDKSGHLKL ADFGTCMkmn kegmvrcdta vgtpdyispe 
       254        264        274        284 
vlksqggdgy ygRECDWWSV GVFLYEMlVg dtpfyadslv 
       294        304        314        324 
gtyskimnhk nsltfpddnd iskeaknlic afltdrevrl 
       334        344        354        364 
grngveeikr hlffkndqwa wetlrdtvap vvPDLSSDID 
       374        384        394 
TSNfddleed kgeeetfpip kaFVGNQLPF VGFTYysn
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None