NEK kinases in all conformations in complex with All ligands

Total number of genes: 11
Total number of chains: 73
Spatial Label Dihedral Label Chains Representative
DFGin BLAminus 11 AF-Q6P3R8-K1A
DFGin BLBminus 1 5M53A
DFGin None 24 6S73A
DFGinter BABtrans 4 4B9DB
DFGinter None 2 2W5BA
DFGout None 11 8SXNA
None None 20 2W5AA
Representatives from each kinase
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Gene UniprotID Protein PDB Resol Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
NEK1 NEK1_HUMAN Serine/threonine-protein kinase Nek1 AF-Q96PY6-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
NEK1 NEK1_HUMAN Serine/threonine-protein kinase Nek1 4APCA 2.1 Inactive DFGinter BABtrans out-none out-out No_ligand No_ligand
NEK1 NEK1_HUMAN Serine/threonine-protein kinase Nek1 4APCB 2.1 Inactive DFGinter BABtrans out-out out-out No_ligand No_ligand
NEK1 NEK1_HUMAN Serine/threonine-protein kinase Nek1 4B9DA 1.9 Inactive DFGinter BABtrans out-none out-out CK7 Type1
NEK1 NEK1_HUMAN Serine/threonine-protein kinase Nek1 4B9DB 1.9 Inactive DFGinter BABtrans out-out out-out CK7 Type1
NEK10 NEK10_HUMAN Serine/threonine-protein kinase Nek10 AF-Q6ZWH5-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
NEK11 NEK11_HUMAN Serine/threonine-protein kinase Nek11 AF-Q8NG66-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 AF-P51955-K1A -1.0 Active DFGin BLAminus out-in in-in No_ligand No_ligand
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 5M53A 1.9 Inactive DFGin BLBminus out-out none-out 7GJ Type1
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XKDA 1.96 Inactive DFGin None out-out none-none T3M Type1
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XKEA 2.203 Inactive DFGin None out-out none-none WI2 Type1
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XKFA 2.35 Inactive DFGin None out-out none-out BX1 Type1
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 5M51A 1.899 Inactive DFGin None out-none none-out NU6 Type1
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 5M57A 2.3 Inactive DFGin None out-none none-out 4SP Type1
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2W5HA 2.33 Inactive DFGinter None out-none none-out No_ligand No_ligand
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2W5BA 2.4 Inactive DFGinter None out-out out-out AGS Type1
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XK3A 2.2 Inactive DFGout None out-out none-out XK3 Type1
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XK4A 2.1 Inactive DFGout None out-out none-out OL2 Type1
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XK8A 2.001 Inactive DFGout None out-out none-out 5R1 Type1
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XNPA 1.98 Inactive DFGout None out-out none-out WCX Type1
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 4AFEA 2.597 Inactive DFGout None out-out none-out GGY Type1
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 4A4XA 2.4 Inactive DFGout None out-out none-out JUP Type1
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2W5AA 1.55 Inactive None None out-out out-out ADP Type1
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2WQOA 2.167 Inactive None None out-out none-none VGK Type1
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XK6A 2.2 Inactive None None out-out none-out EQH Type1
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XK7A 1.992 Inactive None None out-out none-out 30E Type1
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XKCA 2.5 Inactive None None out-none none-none 4VQ Type1
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XNMA 1.85 Inactive None None out-out none-out WGZ Type1
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XNNA 2.5 Inactive None None out-none none-out 430 Type1
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XNOA 1.98 Inactive None None out-out none-out ED8 Type1
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 5M55A 2.4 Inactive None None out-none none-none 7GG Type1
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 6SGDA 2.0 Inactive None None out-none none-none LD5 Type1
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 6SGHA 3.0 Inactive None None out-none none-none LCW Type1
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 6SGIA 2.3 Inactive None None out-out none-out LCB Type1
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 6SGKA 2.0 Inactive None None out-none none-none LCQ Type1
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 6SK9A 2.0 Inactive None None out-none none-none F9N Type1
NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2JAVA 2.2 Inactive None None out-out none-none 5Z5 Type1
NEK3 NEK3_HUMAN Serine/threonine-protein kinase Nek3 AF-P51956-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
NEK4 NEK4_HUMAN Serine/threonine-protein kinase Nek4 AF-P51957-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
NEK5 NEK5_HUMAN Serine/threonine-protein kinase Nek5 AF-Q6P3R8-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
NEK6 NEK6_HUMAN Serine/threonine-protein kinase Nek6 AF-Q9HC98-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 AF-Q8TDX7-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 8EJ4K 3.4 Inactive DFGin None out-none none-none No_ligand No_ligand
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 8EJ4L 3.4 Inactive DFGin None out-none none-none No_ligand No_ligand
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 8EJ4M 3.4 Inactive DFGin None out-none none-none No_ligand No_ligand
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 8EJ4N 3.4 Inactive DFGin None out-none none-none No_ligand No_ligand
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 8EJ4O 3.4 Inactive DFGin None out-none none-none No_ligand No_ligand
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 8EJ4P 3.4 Inactive DFGin None out-none none-none No_ligand No_ligand
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 8EJ4Q 3.4 Inactive DFGin None out-none none-none No_ligand No_ligand
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 8EJ4R 3.4 Inactive DFGin None out-none none-none No_ligand No_ligand
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 8EJ4S 3.4 Inactive DFGin None out-none none-none No_ligand No_ligand
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 8EJ4T 3.4 Inactive DFGin None out-none none-none No_ligand No_ligand
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 2WQMA 2.1 Inactive DFGin None out-out none-none No_ligand No_ligand
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 6S76B 3.38 Inactive DFGin None out-none none-out No_ligand No_ligand
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 6S76C 3.38 Inactive DFGin None out-none none-none No_ligand No_ligand
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 6S73A 3.5 Inactive DFGin None out-none out-out F9N Type1
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 6S73B 3.5 Inactive DFGin None out-out none-out F9N Type1
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 6S73C 3.5 Inactive DFGin None out-none none-none F9N Type1
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 2WQNA 2.3 Inactive DFGin None out-out none-none ADP Type1
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 6S75B 3.3 Inactive DFGin None out-none none-out F9N Type1
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 6S75C 3.3 Inactive DFGin None out-none none-none F9N Type1
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 5DE2A 2.78 Inactive DFGout None out-out none-out No_ligand No_ligand
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 6S75D 3.3 Inactive DFGout None out-none none-none No_ligand No_ligand
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 8SXNA 4.04 Inactive DFGout None out-none out-out No_ligand No_ligand
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 8SXNB 4.04 Inactive DFGout None out-none out-out No_ligand No_ligand
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 6S75A 3.3 Inactive DFGout None out-none none-none F9N Type1
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 6NPYB 3.8 Inactive None None none-none none-none No_ligand No_ligand
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 5DE2B 2.78 Inactive None None out-out none-none No_ligand No_ligand
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 6S73D 3.5 Inactive None None out-none none-none No_ligand No_ligand
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 6S76A 3.38 Inactive None None out-none none-out No_ligand No_ligand
NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 6S76D 3.38 Inactive None None out-none none-none No_ligand No_ligand
NEK8 NEK8_HUMAN Serine/threonine-protein kinase Nek8 AF-Q86SG6-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
NEK9 NEK9_HUMAN Serine/threonine-protein kinase Nek9 AF-Q8TD19-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand

NEK kinases in all conformations in complex with All ligands

Total number of genes: 11
Total number of chains: 73
Spatial Label Dihedral Label Chains Representative
DFGin BLAminus 11 AF-Q6P3R8-K1A
DFGin BLBminus 1 5M53A
DFGin None 24 6S73A
DFGinter BABtrans 4 4B9DB
DFGinter None 2 2W5BA
DFGout None 11 8SXNA
None None 20 2W5AA
Representatives from each kinase
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Gene UniprotID Protein PDB Resol Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens NEK1 NEK1_HUMAN Serine/threonine-protein kinase Nek1 AF-Q96PY6-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens NEK1 NEK1_HUMAN Serine/threonine-protein kinase Nek1 4APCA 2.1 Inactive DFGinter BABtrans out-none out-out No_ligand No_ligand
Homo sapiens NEK1 NEK1_HUMAN Serine/threonine-protein kinase Nek1 4APCB 2.1 Inactive DFGinter BABtrans out-out out-out No_ligand No_ligand
Homo sapiens NEK1 NEK1_HUMAN Serine/threonine-protein kinase Nek1 4B9DA 1.9 Inactive DFGinter BABtrans out-none out-out CK7 Type1
Homo sapiens NEK1 NEK1_HUMAN Serine/threonine-protein kinase Nek1 4B9DB 1.9 Inactive DFGinter BABtrans out-out out-out CK7 Type1
Homo sapiens NEK10 NEK10_HUMAN Serine/threonine-protein kinase Nek10 AF-Q6ZWH5-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens NEK11 NEK11_HUMAN Serine/threonine-protein kinase Nek11 AF-Q8NG66-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 AF-P51955-K1A -1.0 Active DFGin BLAminus out-in in-in No_ligand No_ligand
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 5M53A 1.9 Inactive DFGin BLBminus out-out none-out 7GJ Type1
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XKDA 1.96 Inactive DFGin None out-out none-none T3M Type1
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XKEA 2.203 Inactive DFGin None out-out none-none WI2 Type1
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XKFA 2.35 Inactive DFGin None out-out none-out BX1 Type1
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 5M51A 1.899 Inactive DFGin None out-none none-out NU6 Type1
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 5M57A 2.3 Inactive DFGin None out-none none-out 4SP Type1
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2W5HA 2.33 Inactive DFGinter None out-none none-out No_ligand No_ligand
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2W5BA 2.4 Inactive DFGinter None out-out out-out AGS Type1
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XK3A 2.2 Inactive DFGout None out-out none-out XK3 Type1
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XK4A 2.1 Inactive DFGout None out-out none-out OL2 Type1
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XK8A 2.001 Inactive DFGout None out-out none-out 5R1 Type1
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XNPA 1.98 Inactive DFGout None out-out none-out WCX Type1
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 4AFEA 2.597 Inactive DFGout None out-out none-out GGY Type1
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 4A4XA 2.4 Inactive DFGout None out-out none-out JUP Type1
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2W5AA 1.55 Inactive None None out-out out-out ADP Type1
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2WQOA 2.167 Inactive None None out-out none-none VGK Type1
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XK6A 2.2 Inactive None None out-out none-out EQH Type1
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XK7A 1.992 Inactive None None out-out none-out 30E Type1
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XKCA 2.5 Inactive None None out-none none-none 4VQ Type1
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XNMA 1.85 Inactive None None out-out none-out WGZ Type1
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XNNA 2.5 Inactive None None out-none none-out 430 Type1
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2XNOA 1.98 Inactive None None out-out none-out ED8 Type1
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 5M55A 2.4 Inactive None None out-none none-none 7GG Type1
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 6SGDA 2.0 Inactive None None out-none none-none LD5 Type1
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 6SGHA 3.0 Inactive None None out-none none-none LCW Type1
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 6SGIA 2.3 Inactive None None out-out none-out LCB Type1
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 6SGKA 2.0 Inactive None None out-none none-none LCQ Type1
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 6SK9A 2.0 Inactive None None out-none none-none F9N Type1
Homo sapiens NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2JAVA 2.2 Inactive None None out-out none-none 5Z5 Type1
Homo sapiens NEK3 NEK3_HUMAN Serine/threonine-protein kinase Nek3 AF-P51956-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens NEK4 NEK4_HUMAN Serine/threonine-protein kinase Nek4 AF-P51957-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens NEK5 NEK5_HUMAN Serine/threonine-protein kinase Nek5 AF-Q6P3R8-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens NEK6 NEK6_HUMAN Serine/threonine-protein kinase Nek6 AF-Q9HC98-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 AF-Q8TDX7-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 8EJ4K 3.4 Inactive DFGin None out-none none-none No_ligand No_ligand
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 8EJ4L 3.4 Inactive DFGin None out-none none-none No_ligand No_ligand
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 8EJ4M 3.4 Inactive DFGin None out-none none-none No_ligand No_ligand
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 8EJ4N 3.4 Inactive DFGin None out-none none-none No_ligand No_ligand
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 8EJ4O 3.4 Inactive DFGin None out-none none-none No_ligand No_ligand
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 8EJ4P 3.4 Inactive DFGin None out-none none-none No_ligand No_ligand
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 8EJ4Q 3.4 Inactive DFGin None out-none none-none No_ligand No_ligand
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 8EJ4R 3.4 Inactive DFGin None out-none none-none No_ligand No_ligand
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 8EJ4S 3.4 Inactive DFGin None out-none none-none No_ligand No_ligand
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 8EJ4T 3.4 Inactive DFGin None out-none none-none No_ligand No_ligand
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 2WQMA 2.1 Inactive DFGin None out-out none-none No_ligand No_ligand
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 6S76B 3.38 Inactive DFGin None out-none none-out No_ligand No_ligand
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 6S76C 3.38 Inactive DFGin None out-none none-none No_ligand No_ligand
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 6S73A 3.5 Inactive DFGin None out-none out-out F9N Type1
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 6S73B 3.5 Inactive DFGin None out-out none-out F9N Type1
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 6S73C 3.5 Inactive DFGin None out-none none-none F9N Type1
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 2WQNA 2.3 Inactive DFGin None out-out none-none ADP Type1
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 6S75B 3.3 Inactive DFGin None out-none none-out F9N Type1
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 6S75C 3.3 Inactive DFGin None out-none none-none F9N Type1
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 5DE2A 2.78 Inactive DFGout None out-out none-out No_ligand No_ligand
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 6S75D 3.3 Inactive DFGout None out-none none-none No_ligand No_ligand
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 8SXNA 4.04 Inactive DFGout None out-none out-out No_ligand No_ligand
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 8SXNB 4.04 Inactive DFGout None out-none out-out No_ligand No_ligand
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 6S75A 3.3 Inactive DFGout None out-none none-none F9N Type1
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 6NPYB 3.8 Inactive None None none-none none-none No_ligand No_ligand
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 5DE2B 2.78 Inactive None None out-out none-none No_ligand No_ligand
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 6S73D 3.5 Inactive None None out-none none-none No_ligand No_ligand
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 6S76A 3.38 Inactive None None out-none none-out No_ligand No_ligand
Homo sapiens NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 6S76D 3.38 Inactive None None out-none none-none No_ligand No_ligand
Homo sapiens NEK8 NEK8_HUMAN Serine/threonine-protein kinase Nek8 AF-Q86SG6-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens NEK9 NEK9_HUMAN Serine/threonine-protein kinase Nek9 AF-Q8TD19-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand

NEK kinases in all conformations in complex with All ligands

Total number of genes: 0
Total number of chains: 0
Spatial Label Dihedral Label Chains Representative
Representatives from each kinase
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Gene UniprotID Protein PDB Reso Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type