| Chain id | Activity_label | Spatial_label | Dihedral_label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|
| A | Inactive | DFGin | BLBminus | in-in | in-in | STU | Type1 | 164 - 458 | 5 |
| B | Inactive | DFGin | BLBminus | in-out | in-in | STU | Type1 | 164 - 458 | 5 |
| C | Active | DFGin | BLAminus | in-in | in-in | STU | Type1 | 164 - 458 | 4 |
| D | Active | DFGin | BLAminus | in-in | in-in | STU | Type1 | 164 - 460 | 5 |
Representative sequence - Chain D
163 173 183 193
enkslevsdt RFHSFSFYEL KNVTNNFDER PISVGGNKMG
203 213 223 233
EGGFGVVYKG YVNNTTVAVK KLaamvditt eELKQQFDQE
243 253 263 273
IKVMAKCQHE NLVELLGFSS DGDDLCLVYV YMPNGSLLDR
283 293 303 313
LSCLDGTPPL SWHMRCKIAQ GAANGINFLH ENHHIHRDIK
323 333 343 353
SANILLDEAF TAKISDFGLA RASEkfaqtV MTSRIVGTTA
363 373 383 393
YMAPEALRGE ITPKSDIYSF GVVLLEIITG LPAVDEHREP
403 413 423 433
QLLLDIKEEI EDEEKTIEDY IDKKMNDADS TSVEAMYSVA
443 453
SQCLHEKKNK RPDIKKVQQL LQEMTAS