STK24 (Serine/threonine-protein kinase 24)

Group: STE
Uniprot: STK24_HUMAN
Domain boundary: 36 - 286


Total number of chains: 48
Spatial Dihedral Chains Representative
DFGin BLAminus 29 AF-Q9Y6E0-K1A
DFGin BLBminus 16 3ZHPC
DFGin BLBplus 1 8QLQA
DFGin None 1 4O27B
None None 1 3CKWA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
AF-Q9Y6E0-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 28 - 294 None None 0
3A7FA 1.55 Active DFGin BLAminus in-in in-in No_ligand No_ligand 18 - 310 None X190 6
3A7GA 2.0 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 18 - 310 None X190 0
3A7GB 2.0 Inactive DFGin BLAminus out-out in-in No_ligand No_ligand 17 - 310 None X190 0
4U8ZA 1.63 Active DFGin BLAminus in-in in-in 3FE Type1 24 - 310 None X190 0
4W8DA 1.77 Active DFGin BLAminus in-in in-in 3JA Type1 24 - 310 None X190 0
4W8EA 1.79 Active DFGin BLAminus in-in in-in 3JB Type1 24 - 311 None X190 0
3A7HA 1.96 Inactive DFGin BLAminus in-out in-in ATP Type1 18 - 310 None X190 0
3A7HB 1.96 Inactive DFGin BLAminus out-out in-in ATP Type1 17 - 310 None X190 0
3A7IA 1.45 Active DFGin BLAminus in-in in-in ADE Type1 25 - 311 None X190 0
3A7JA 1.5 Active DFGin BLAminus in-in in-in ADP Type1 25 - 311 None X190 0
3CKXA 2.7 Inactive DFGin BLAminus in-out in-in STU Type1 32 - 310 None X190 0
4QMLA 1.882 Active DFGin BLAminus in-in in-in ANP Type1 30 - 310 None X190 0
4QMMA 1.852 Active DFGin BLAminus in-in in-in 35R Type1 18 - 309 None X190 0
4QMNA 2.091 Active DFGin BLAminus in-in in-in DB8 Type1 27 - 310 None X190 0
4QMOA 1.898 Active DFGin BLAminus in-in in-in 34L Type1 18 - 309 None X190 0
4QMPA 2.0 Active DFGin BLAminus in-in in-in DKI Type1 18 - 310 None X190 0
4QMQA 1.769 Active DFGin BLAminus in-in in-in 34U Type1 18 - 310 None X190 0
4QMSA 1.883 Inactive DFGin BLAminus in-out in-in 1N1 Type1 27 - 310 None X190 0
4QMTA 1.5 Active DFGin BLAminus in-in in-in H1N Type1 27 - 311 None X190 0
4QMUA 1.546 Active DFGin BLAminus in-in in-in SKE Type1 24 - 310 None X190 0
4QMVA 2.4 Active DFGin BLAminus in-in in-in 34W Type1 19 - 310 None X190 0
4QMXA 1.882 Active DFGin BLAminus in-in in-in H8H Type1 24 - 311 None X190 0
4QMYA 1.883 Active DFGin BLAminus in-in in-in STU Type1 20 - 310 None X190 0
4QMZA 1.88 Active DFGin BLAminus in-in in-in B49 Type1 25 - 311 None X190 0
4QNAA 1.849 Active DFGin BLAminus in-in in-in X11 Type1 27 - 311 None X190 0
4QO9A 2.2 Active DFGin BLAminus in-in in-in 627 Type1 30 - 310 None X190 0
4QO9B 2.2 Active DFGin BLAminus in-in in-in 627 Type1 25 - 310 None X190 0
4QMWA 1.6 Active DFGin BLAminus in-in in-in KS1 Type1.5_Back 24 - 310 None X190 0
3ZHPC 2.9 Inactive DFGin BLBminus out-out out-out No_ligand No_ligand 31 - 300 None None 3
3ZHPD 2.9 Inactive DFGin BLBminus out-none out-out No_ligand No_ligand 32 - 301 None None 6
8BZIA 1.72 Inactive DFGin BLBminus out-out none-none SJL Type1.5_Back 26 - 301 None None 15
8BZJA 2.52 Inactive DFGin BLBminus out-out none-none SJX Type1.5_Back 26 - 301 None None 15
7B30A 2.1 Inactive DFGin BLBminus out-out none-none 59T Type1.5_Front 26 - 301 None None 15
7B31A 1.8 Inactive DFGin BLBminus out-out none-none SQ8 Type1.5_Front 26 - 301 None None 15
7B32A 1.75 Inactive DFGin BLBminus out-out none-none SQQ Type1.5_Front 26 - 301 None None 15
7B33A 1.9 Inactive DFGin BLBminus out-out none-none SQE Type1.5_Front 26 - 301 None None 15
7B34A 2.1 Inactive DFGin BLBminus out-out none-none SQK Type1.5_Front 26 - 301 None None 15
7B35A 2.4 Inactive DFGin BLBminus out-out none-none SQB Type1.5_Front 26 - 301 None None 15
7B35B 2.4 Inactive DFGin BLBminus out-out none-none SQB Type1.5_Front 26 - 301 None None 15
8BZJB 2.52 Inactive DFGin BLBminus out-out none-none SJX Type1.5_Front 26 - 301 None None 15
8QLRA 1.85 Inactive DFGin BLBminus out-out none-none VYN Type1.5_Front 26 - 301 None None 15
8QLRB 1.85 Inactive DFGin BLBminus out-out none-none VYN Type1.5_Front 26 - 301 None None 15
8QLSA 1.61 Inactive DFGin BLBminus out-out none-none VYH Type1.5_Front 26 - 301 None None 15
8QLTA 1.47 Inactive DFGin BLBminus out-out none-none VZ2 Type1.5_Front 25 - 301 None None 15
8QLQA 1.64 Inactive DFGin BLBplus out-out out-out VY0 Type1 26 - 301 None None 0
4O27B 3.185 Inactive DFGin None in-in in-in ADP Type1 30 - 309 T190E None 0
3CKWA 1.96 Inactive None None in-in none-in No_ligand No_ligand 32 - 310 None None 15

STK24 (Serine/threonine-protein kinase 24)

Group: STE
Total number of chains: 48
Spatial Dihedral Chains Representative
DFGin BLAminus 29 AF-Q9Y6E0-K1A
DFGin BLBminus 16 3ZHPC
DFGin BLBplus 1 8QLQA
DFGin None 1 4O27B
None None 1 3CKWA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens STK24_HUMAN AF-Q9Y6E0-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 28 - 294 None None 0
Homo sapiens STK24_HUMAN 3A7FA 1.55 Active DFGin BLAminus in-in in-in No_ligand No_ligand 18 - 310 None X190 6
Homo sapiens STK24_HUMAN 3A7GA 2.0 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 18 - 310 None X190 0
Homo sapiens STK24_HUMAN 3A7GB 2.0 Inactive DFGin BLAminus out-out in-in No_ligand No_ligand 17 - 310 None X190 0
Homo sapiens STK24_HUMAN 4U8ZA 1.63 Active DFGin BLAminus in-in in-in 3FE Type1 24 - 310 None X190 0
Homo sapiens STK24_HUMAN 4W8DA 1.77 Active DFGin BLAminus in-in in-in 3JA Type1 24 - 310 None X190 0
Homo sapiens STK24_HUMAN 4W8EA 1.79 Active DFGin BLAminus in-in in-in 3JB Type1 24 - 311 None X190 0
Homo sapiens STK24_HUMAN 3A7HA 1.96 Inactive DFGin BLAminus in-out in-in ATP Type1 18 - 310 None X190 0
Homo sapiens STK24_HUMAN 3A7HB 1.96 Inactive DFGin BLAminus out-out in-in ATP Type1 17 - 310 None X190 0
Homo sapiens STK24_HUMAN 3A7IA 1.45 Active DFGin BLAminus in-in in-in ADE Type1 25 - 311 None X190 0
Homo sapiens STK24_HUMAN 3A7JA 1.5 Active DFGin BLAminus in-in in-in ADP Type1 25 - 311 None X190 0
Homo sapiens STK24_HUMAN 3CKXA 2.7 Inactive DFGin BLAminus in-out in-in STU Type1 32 - 310 None X190 0
Homo sapiens STK24_HUMAN 4QMLA 1.882 Active DFGin BLAminus in-in in-in ANP Type1 30 - 310 None X190 0
Homo sapiens STK24_HUMAN 4QMMA 1.852 Active DFGin BLAminus in-in in-in 35R Type1 18 - 309 None X190 0
Homo sapiens STK24_HUMAN 4QMNA 2.091 Active DFGin BLAminus in-in in-in DB8 Type1 27 - 310 None X190 0
Homo sapiens STK24_HUMAN 4QMOA 1.898 Active DFGin BLAminus in-in in-in 34L Type1 18 - 309 None X190 0
Homo sapiens STK24_HUMAN 4QMPA 2.0 Active DFGin BLAminus in-in in-in DKI Type1 18 - 310 None X190 0
Homo sapiens STK24_HUMAN 4QMQA 1.769 Active DFGin BLAminus in-in in-in 34U Type1 18 - 310 None X190 0
Homo sapiens STK24_HUMAN 4QMSA 1.883 Inactive DFGin BLAminus in-out in-in 1N1 Type1 27 - 310 None X190 0
Homo sapiens STK24_HUMAN 4QMTA 1.5 Active DFGin BLAminus in-in in-in H1N Type1 27 - 311 None X190 0
Homo sapiens STK24_HUMAN 4QMUA 1.546 Active DFGin BLAminus in-in in-in SKE Type1 24 - 310 None X190 0
Homo sapiens STK24_HUMAN 4QMVA 2.4 Active DFGin BLAminus in-in in-in 34W Type1 19 - 310 None X190 0
Homo sapiens STK24_HUMAN 4QMXA 1.882 Active DFGin BLAminus in-in in-in H8H Type1 24 - 311 None X190 0
Homo sapiens STK24_HUMAN 4QMYA 1.883 Active DFGin BLAminus in-in in-in STU Type1 20 - 310 None X190 0
Homo sapiens STK24_HUMAN 4QMZA 1.88 Active DFGin BLAminus in-in in-in B49 Type1 25 - 311 None X190 0
Homo sapiens STK24_HUMAN 4QNAA 1.849 Active DFGin BLAminus in-in in-in X11 Type1 27 - 311 None X190 0
Homo sapiens STK24_HUMAN 4QO9A 2.2 Active DFGin BLAminus in-in in-in 627 Type1 30 - 310 None X190 0
Homo sapiens STK24_HUMAN 4QO9B 2.2 Active DFGin BLAminus in-in in-in 627 Type1 25 - 310 None X190 0
Homo sapiens STK24_HUMAN 4QMWA 1.6 Active DFGin BLAminus in-in in-in KS1 Type1.5_Back 24 - 310 None X190 0
Homo sapiens STK24_HUMAN 3ZHPC 2.9 Inactive DFGin BLBminus out-out out-out No_ligand No_ligand 31 - 300 None None 3
Homo sapiens STK24_HUMAN 3ZHPD 2.9 Inactive DFGin BLBminus out-none out-out No_ligand No_ligand 32 - 301 None None 6
Homo sapiens STK24_HUMAN 8BZIA 1.72 Inactive DFGin BLBminus out-out none-none SJL Type1.5_Back 26 - 301 None None 15
Homo sapiens STK24_HUMAN 8BZJA 2.52 Inactive DFGin BLBminus out-out none-none SJX Type1.5_Back 26 - 301 None None 15
Homo sapiens STK24_HUMAN 7B30A 2.1 Inactive DFGin BLBminus out-out none-none 59T Type1.5_Front 26 - 301 None None 15
Homo sapiens STK24_HUMAN 7B31A 1.8 Inactive DFGin BLBminus out-out none-none SQ8 Type1.5_Front 26 - 301 None None 15
Homo sapiens STK24_HUMAN 7B32A 1.75 Inactive DFGin BLBminus out-out none-none SQQ Type1.5_Front 26 - 301 None None 15
Homo sapiens STK24_HUMAN 7B33A 1.9 Inactive DFGin BLBminus out-out none-none SQE Type1.5_Front 26 - 301 None None 15
Homo sapiens STK24_HUMAN 7B34A 2.1 Inactive DFGin BLBminus out-out none-none SQK Type1.5_Front 26 - 301 None None 15
Homo sapiens STK24_HUMAN 7B35A 2.4 Inactive DFGin BLBminus out-out none-none SQB Type1.5_Front 26 - 301 None None 15
Homo sapiens STK24_HUMAN 7B35B 2.4 Inactive DFGin BLBminus out-out none-none SQB Type1.5_Front 26 - 301 None None 15
Homo sapiens STK24_HUMAN 8BZJB 2.52 Inactive DFGin BLBminus out-out none-none SJX Type1.5_Front 26 - 301 None None 15
Homo sapiens STK24_HUMAN 8QLRA 1.85 Inactive DFGin BLBminus out-out none-none VYN Type1.5_Front 26 - 301 None None 15
Homo sapiens STK24_HUMAN 8QLRB 1.85 Inactive DFGin BLBminus out-out none-none VYN Type1.5_Front 26 - 301 None None 15
Homo sapiens STK24_HUMAN 8QLSA 1.61 Inactive DFGin BLBminus out-out none-none VYH Type1.5_Front 26 - 301 None None 15
Homo sapiens STK24_HUMAN 8QLTA 1.47 Inactive DFGin BLBminus out-out none-none VZ2 Type1.5_Front 25 - 301 None None 15
Homo sapiens STK24_HUMAN 8QLQA 1.64 Inactive DFGin BLBplus out-out out-out VY0 Type1 26 - 301 None None 0
Homo sapiens STK24_HUMAN 4O27B 3.185 Inactive DFGin None in-in in-in ADP Type1 30 - 309 T190E None 0
Homo sapiens STK24_HUMAN 3CKWA 1.96 Inactive None None in-in none-in No_ligand No_ligand 32 - 310 None None 15

STK24 (Serine/threonine-protein kinase 24)

No non-human structures known.