5KO1

MLKL (Mixed lineage kinase domain-like protein)
Pseudokinase
Group: OTHER
Uniprot: MLKL_HUMAN
Organism: Homo sapiens
Domain boundary: 201 - 468
Resolu: 2.16

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLBminus in-in out-out 6UY Type1 192 - 470 14
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       198        208        218        228 
gseQIKEIKK EQLSGSPWIL LRENEVSTLY KGEYHRAPVA 
       238        248        258        268 
IKVFKKLQAG SIAIVRQTFN KEIKTMKKFE SPNILRIFGI 
       278        288        298        308 
CIDETVTPPQ FSIVMEYCEL GTLRELLDRE KDLTLGKRMV 
       318        328        338        348 
LVLGAARGLY RLHHSEAPEL HGKIRSSNFL VTQGYQVKLA 
       358        368        378        388 
GFELRKtqts mslgttraat DRVKSTAYLS PQELEDVFYQ 
       398        408        418        428 
YDVKSEIYSF GIVLWEIATG DIPFQGCNSE KIRKLVAVKR 
       438        448        458        468 
QQEPLGEDCP SELREIIDEC RAHDPSVRPS VDEILKKLST 

FSk
Lower-case residues are disordered in structure.
Mutations: E366A,K367A
Phosphorylation: None