7P3V

BRAF (Serine/threonine-protein kinase B-raf)
Group: TKL
Uniprot: BRAF_HUMAN
Organism: Homo sapiens
Domain boundary: 457 - 716
Resolu: 2.37

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLBminus out-out none-out 5I4 Type1.5_Back 448 - 719 17
B Inactive DFGin BLBminus out-out out-out 5I4 Type1.5_Back 448 - 719 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       456        466        476        486 
fDDWEIPDGQ ITVGQRIGSG SFGTVYKGKW HGDVAVKMLN 
       496        506        516        526 
VTAPTPQQLQ AFKNEVGVLR KTRHVNILLF MGYSTKPQLA 
       536        546        556        566 
IVTQWCEGSS LYHHLHASET KFEMKKLIDI ARQTARGMDY 
       576        586        596        606 
LHAKSIIHRD LKSNNIFLHE DNTVKIGDFG LATEKSRWSG 
       616        626        636        646 
SHQFEQLSGS ILWMAPEVIR MQDSNPYSFQ SDVYAFGIVL 
       656        666        676        686 
YELMTGQLPY SNINNRDQII EMVGRGSLSP DLSKVRSNCP 
       696        706        716 
KRMKRLMAEC LKKKRDERPS FPRILAEIEE LARea
Lower-case residues are disordered in structure.
Mutations: V600E
Phosphorylation: None