| Chain id | Activity_label | Spatial_label | Dihedral_label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|
| A | Inactive | DFGin | BLBminus | in-in | out-out | KRE | Type1 | 5 - 316 | 16 |
| B | None | DFGin | BLAminus | in-out | in-none | KRE | Type1 | 5 - 315 | 14 |
| C | Inactive | DFGin | BLBminus | in-in | out-out | KRE | Type1 | 5 - 315 | 16 |
| D | Inactive | DFGin | BLAminus | in-in | in-out | KRE | Type1 | 5 - 316 | 17 |
Representative sequence - Chain D
10 20 30 40
smgeAICSAL PTIPYHKLAD LRYLSRGASG TVSSARHADW
50 60 70 80
RVQVAVKHLH IHTPLLDSER KDVLREAEIL HKARFSYILP
90 100 110 120
ILGICNEPEF LGIVTEYMPN GSLNELLHRK TEYPDVAWPL
130 140 150 160
RFRILHEIAL GVNYLHNMTP PLLHHDLKTQ NILLDNEFHV
170 180 190 200
KIADFGLSKW rmmslsqsrs sksapegGTI IYMPPENYep
210 220 230 240
gqksrASIKH DIYSYAVITW EVLSRKQPFE DVTNPLQIMY
250 260 270 280
SVSQGHRPVI NEESLPYDIP HRARMISLIE SGWAQNPDER
290 300 310
PSFLKCLIEL EPVLRTFEEI TFLEAVIQLK KTKLQSv