6O5Z

MLKL (Mixed lineage kinase domain-like protein)
Pseudokinase
Group: OTHER
Uniprot: MLKL_HUMAN
Organism: Homo sapiens
Domain boundary: 201 - 468
Resolu: 2.285

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus in-in out-out No_ligand No_ligand 191 - 470 9
B Inactive DFGout None in-out none-out LN4 Type2 190 - 467 12
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       194        204        214        224 
gamgsQEQIK EIKKEQLSGS PWILLRENEV STLYKGEYHR 
       234        244        254        264 
APVAIKVFKK lqagsiAIVR QTFNKEIKTM KKFESPNILR 
       274        284        294        304 
IFGICIDETV TPPQFSIVME YCELGTLREL LDREKDLTLG 
       314        324        334        344 
KRMVLVLGAA RGLYRLHHSE APELHGKIRS SNFLVTQGYQ 
       354        364        374        384 
VKLAGFelrk tqtsmslgTT REKTDRVKST AYLSPQELED 
       394        404        414        424 
VFYQYDVKSE IYSFGIVLWE IATGDIPFQG CNSEKIRKLV 
       434        444        454        464 
AVKRQQEPLG EDCPSELREI IDECRAHDPS VRPSVDEILK 

KLStfsk
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None