AF-Q76MJ5-K1

ERN2 (Serine/threonine-protein kinase/endoribonuclease IRE2)
Group: OTHER
Uniprot: ERN2_HUMAN
Organism: Homo sapiens
Domain boundary: 518 - 781
Resolu: -1.0

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in No_ligand No_ligand 510 - 789 0
Representative sequence - Chain A
519 529 539 549
EQLTVVGKIS FNPKDVLGRG AGGTFVFRGQ FEGRAVAVKR
559 569 579 589
LLRECFGLVR REVQLLQESD RHPNVLRYFC TERGPQFHYI
599 609 619 629
ALELCRASLQ EYVENPDLDR GGLEPEVVLQ QLMSGLAHLH
639 649 659 669
SLHIVHRDLK PGNILITGPD SQGLGRVVLS DFGLCKKLPA
679 689 699 709
GRCSFSLHSG IPGTEGWMAP ELLQLLPPDS PTSAVDIFSA
719 729 739 749
GCVFYYVLSG GSHPFGDSLY RQANILTGAP CLAHLEEEVH
759 769 779 789
DKVVARDLVG AMLSPLPQPR PSAPQVLAHP FFWSRAKQLQ


Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None