Protein kinases in complex with 38O (Dovitinib)

Total number of genes: 5
Total number of chains: 14
Spatial Dihedral Chains Representative
DFGin BLAminus 1 7AKGA
DFGin BLAplus 7 5A46B
DFGin None 4 7QQ6A
None None 2 5OWQB
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
CAMK STK17B ST17B_HUMAN Serine/threonine-protein kinase 17B 7AKGA 2.08 Inactive DFGin BLAminus in-in in-out 38O Type1
OTHER EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QQ6A 2.8 Inactive DFGin None out-out none-out 38O Type1
OTHER EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QQ6B 2.8 Inactive DFGin None out-out none-out 38O Type1
OTHER EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QQ6C 2.8 Inactive DFGin None out-out out-out 38O Type1
OTHER EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QQ6D 2.8 Inactive DFGin None out-out out-none 38O Type1
STE STK10 STK10_HUMAN Serine/threonine-protein kinase 10 5OWQA 2.7 Inactive None None out-none none-none 38O Type1
STE STK10 STK10_HUMAN Serine/threonine-protein kinase 10 5OWQB 2.7 Inactive None None out-out none-none 38O Type1
TYR FGFR1 FGFR1_HUMAN Fibroblast growth factor receptor 1 5AM7A 1.957 Inactive DFGin BLAplus in-in out-out 38O Type1
TYR FGFR1 FGFR1_HUMAN Fibroblast growth factor receptor 1 5AM7B 1.957 Inactive DFGin BLAplus in-in out-out 38O Type1
TYR FGFR1 FGFR1_HUMAN Fibroblast growth factor receptor 1 5AM6A 1.96 Inactive DFGin BLAplus in-in out-out 38O Type1
TYR FGFR1 FGFR1_HUMAN Fibroblast growth factor receptor 1 5AM6B 1.96 Inactive DFGin BLAplus in-in out-out 38O Type1
TYR FGFR1 FGFR1_HUMAN Fibroblast growth factor receptor 1 5A46A 2.63 Inactive DFGin BLAplus in-in out-out 38O Type1
TYR FGFR1 FGFR1_HUMAN Fibroblast growth factor receptor 1 5A46B 2.63 Inactive DFGin BLAplus in-in out-out 38O Type1
TYR FGFR4 FGFR4_HUMAN Fibroblast growth factor receptor 4 4TYIA 3.4 Inactive DFGin BLAplus in-out out-out 38O Type1

Protein kinases in complex with 38O

Total number of genes: 5
Total number of chains: 14
Spatial Dihedral Chains Representative
DFGin BLAminus 1 7AKGA
DFGin BLAplus 7 5A46B
DFGin None 4 7QQ6A
None None 2 5OWQB
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens CAMK STK17B ST17B_HUMAN Serine/threonine-protein kinase 17B 7AKGA 2.08 Inactive DFGin BLAminus in-in in-out 38O Type1
Homo sapiens OTHER EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QQ6A 2.8 Inactive DFGin None out-out none-out 38O Type1
Homo sapiens OTHER EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QQ6B 2.8 Inactive DFGin None out-out none-out 38O Type1
Homo sapiens OTHER EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QQ6C 2.8 Inactive DFGin None out-out out-out 38O Type1
Homo sapiens OTHER EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QQ6D 2.8 Inactive DFGin None out-out out-none 38O Type1
Homo sapiens STE STK10 STK10_HUMAN Serine/threonine-protein kinase 10 5OWQA 2.7 Inactive None None out-none none-none 38O Type1
Homo sapiens STE STK10 STK10_HUMAN Serine/threonine-protein kinase 10 5OWQB 2.7 Inactive None None out-out none-none 38O Type1
Homo sapiens TYR FGFR1 FGFR1_HUMAN Fibroblast growth factor receptor 1 5AM7A 1.957 Inactive DFGin BLAplus in-in out-out 38O Type1
Homo sapiens TYR FGFR1 FGFR1_HUMAN Fibroblast growth factor receptor 1 5AM7B 1.957 Inactive DFGin BLAplus in-in out-out 38O Type1
Homo sapiens TYR FGFR1 FGFR1_HUMAN Fibroblast growth factor receptor 1 5AM6A 1.96 Inactive DFGin BLAplus in-in out-out 38O Type1
Homo sapiens TYR FGFR1 FGFR1_HUMAN Fibroblast growth factor receptor 1 5AM6B 1.96 Inactive DFGin BLAplus in-in out-out 38O Type1
Homo sapiens TYR FGFR1 FGFR1_HUMAN Fibroblast growth factor receptor 1 5A46A 2.63 Inactive DFGin BLAplus in-in out-out 38O Type1
Homo sapiens TYR FGFR1 FGFR1_HUMAN Fibroblast growth factor receptor 1 5A46B 2.63 Inactive DFGin BLAplus in-in out-out 38O Type1
Homo sapiens TYR FGFR4 FGFR4_HUMAN Fibroblast growth factor receptor 4 4TYIA 3.4 Inactive DFGin BLAplus in-out out-out 38O Type1

Protein kinases in complex with 38O

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type